Australia Thirty-year Menzies melioidosis study finds cases are rising but mortality has tumbled

03:36  23 july  2021
03:36  23 july  2021 Source:   abc.net.au

Tucker Carlson Hyped These Fringe COVID Theories. The Science Just Fell Apart.

  Tucker Carlson Hyped These Fringe COVID Theories. The Science Just Fell Apart. Fox News host Tucker Carlson and his fellow COVID-19 deniers have pounced on two controversial claims recently, arguing that face masks endanger children and that a drug used for parasitic worms could potentially treat COVID-19. Some have cited two scientific studies to back them up. The issue: Those studies have since been retracted. On Friday, JAMA Pediatrics retracted a study claiming face masks could expose children to increased levels of carbon dioxide, one Carlson had covered extensively on his show Tucker Carlson Tonight.It adds to the widespread concern about the role public figures like Carlson have had on the U.S.

New research shows the mortality rate for melioidosis has declined. But the number of cases being diagnosed is steadily increasing. Experts say people with existing conditions such as diabetes and heavy drinkers are at the highest risk. Mr Creek remembers that day — and the weeks leading up to it — well. The researchers found the number of cases diagnosed each year trended upwards, rising from six in the first year of their study to 41 cases in the final one (there was also a spike of 96 cases over the 2011-12 wet season following Cyclone Grant).

Cases of melioidosis , which is also known as Whitmore's disease, are under-reported because its symptoms - including abscesses, fever and sepsis - are quite unspecific. Proper diagnosis also requires laboratory equipment that is scarce in developing countries, where Burkholderia pseudomallei, the When accurately diagnosed and treated properly, melioidosis death rates can be as low as 10 percent, but without the right medication they can rise to as high as 70 percent. When untreated, the disease kills up to 9 patients in 10. The authors of the study say their model predicts that melioidosis killed

On the day Bob Creek was due to retire, he was in Royal Darwin Hospital being treated for a potentially deadly soil-borne disease.

Mr Creek remembers that day — and the weeks leading up to it — well.

On May 4, 2017, he fell down a verandah footing and scraped his leg.

"It was a bit of a muddy hole, and I took some skin off my shin — nothing out of the ordinary," Mr Creek said.

Six weeks later, and with his wound no closer to healing, Mr Creek learned he had acquired a potentially lethal disease when he came into contact with the mud.

Melioidosis is caused by a bacterium living in the soil that comes to the surface during heavy rainfall.

Moon ‘wobble’, rising seas to cause flooding surge: NASA study

  Moon ‘wobble’, rising seas to cause flooding surge: NASA study The combination of the Moon’s natural cycle and climate change is projected to cause flooding to surge in the 2030s.The record flooding is projected to begin in the 2030s and last 10 years, according to the study, which focused on the phenomena’s effect in the US.

Melioidosis has a wide range of radiological manifestations making it a mimicker. Diagnosis requires a high index of clinical suspicion in patients with septicemia or a fever of unknown origin living in or with a travel history to endemic areas. We present a pictorial review of the radiological manifestations of melioidosis , which is a useful knowledge for radiologists to help arrive at an early diagnosis. In this pictorial review, we present the radiological manifestations chosen from 139 patients with culture proven melioidosis .

"What we know about coronavirus from 30 years of experience is that a coronavirus vaccine has a unique peculiarity, which is any attempt at making the vaccine has resulted in the creation of a class of antibodies that actually make vaccinated people sicker when they ultimately suffer exposure to the And, while the cost of living has been rising steadily in the first 50 years after WWII in industrialized countries, it has been rather stagnant over the last couple of decades. To the contrary, in some cases - US, Europe - a rather deflationary trend has appeared. A clear sign for it, is negative interest rates in

"My knowledge of melioidosis was that death commonly followed, and I thought at that point I was a candidate," Mr Creek said.

New research, published today in The Lancet Infectious Diseases medical journal, has tracked the disease as it has moved out of medical obscurity.

It shows that although fewer people in Darwin are dying from the disease, the number of cases being diagnosed is steadily increasing.

'Melioidosis was gravely feared'

Researchers followed patients who had been diagnosed with the disease in Darwin over the past 30 years, tracking their age, location and any pre-existing health conditions such as diabetes or chronic lung disease.

Lead author Bart Currie from the Menzies School of Health Research said the mortality rate for people diagnosed with melioidosis plummeted over the lifetime of the study.

US life expectancy fell sharply in 2020 due to Covid

  US life expectancy fell sharply in 2020 due to Covid Average US life expectancy fell by 1.5 years in 2020, a sharp decline driven by the Covid-19 pandemic affecting males and communities of color the most, new data showed Wednesday. Life expectancy at birth for the total US population was 77.3 years, down from 78.8 in 2019, and the lowest it has been since 2003, said a report by the US Centers for Disease Control and Prevention (CDC). The significant fall also bucks a trend of steady increase in the post-World War II period, albeit with small decreases in some years.Among males, the figure was 74.5 years, a decrease of 1.8 years, and among females it was 80.2 years, a decline of 1.2 years.

[15] studied the liver function tests of 175 diabetic patients without known chronic liver disease; 57% were found to have at least one abnormal LFT, and 27% had at least two abnormal LFTs. Percentage decrease in eGFR between the first and third year post-transplant is also significantly predictive of patient survival, and a drop in eGFR ! 30 % has been associated with a 2.2-fold increased mortality in KTRs [13]. Besides the positive effects on graft function preservation [16], PA has been shown to reduce the risk of CVD [17], metabolic disease and diabetes [9,18], and to facilitate a better

The case fatality rate is the number of confirmed deaths divided by the number of confirmed cases . This chart here plots the CFR calculated in just that way. During an outbreak – and especially when the total number of cases is not known – one has to be very careful in interpreting the CFR. So when we compare the CFR between different countries, the differences do not only reflect rates of mortality , but also differences in the scale of testing efforts. When some people are currently sick and will die of the disease, but have not died yet, the CFR will underestimate the true risk of death.

"When we first started the study, melioidosis was gravely feared in the Top End because it was causing such high mortality," he said.

Over the first five years of the study, 31 per cent of people diagnosed with melioidosis in Darwin died from the disease, compared with 6 per cent of people who died from the disease in the last five years of the study.

Professor Currie put this down to four key reasons: early diagnosis, access to new antibiotics for treatment, increased public awareness and the high level of care given to critically ill patients.

"If you can make that diagnosis within 24 to 48 hours of a person's illness or presentation then you have an opportunity to do the things that can to save their lives," he said.

University of Western Australia senior research fellow Mitali Sarkar-Tyson agreed rapid diagnosis played a major role in improving survival rates, as did awareness.

Survey finds alarming rise in severe emotional distress among WA school students

  Survey finds alarming rise in severe emotional distress among WA school students A survey of more than 24,000 students in Western Australia has found a concerning number of adolescents are experiencing emotional distress — likely exacerbated by the COVID pandemic.The survey of more than 24,000 students across 79 public schools found around 40 per cent of secondary students were experiencing moderate to high levels of emotional distress.

She said her experience of 30 years in the field showed child abuse was widespread, not just sexual violence but ‘digital’ abuse which took place over phone or computer videos without the abuser or the victim being in the same room. “Our estimate is that in every German classroom between two and four children are abused, not all severely, terribly sexaully abused but also by the overstepping of digital boundaries,” she said. Those digital boundaries prove highly problematic to police investigators.

VAERS has received a lot of criticism over the years , some of it founded. Some critics have argued for a long time that VAERS undercounts vaccine injuries. A report submitted to the Department of Health and Human Services in 2010 concluded that "fewer than one percent of vaccine adverse events are Contrast that with what is happening now. This time, our health authorities have reserved their energy for anyone who dares to question vaccines. LifeSiteNews, a nonprofit news organization, just found itself permanently banned from Facebook. Why? Because it reported government numbers from the

"There's also been a lot of work done to educate medical professions about the need to routinely test for melioidosis," she said.

"The disease itself has flu-like symptoms so it's quite often misdiagnosed."

The study shows cases of melioidosis in Darwin directly correlate with rainfall, with 80 per cent of infections diagnosed during the wet season.

More cases of the disease

The researchers found the number of cases diagnosed each year trended upwards, rising from six in the first year of their study to 41 cases in the final one (there was also a spike of 96 cases over the 2011-12 wet season following Cyclone Grant).

The number of cases per 100,000 people in Darwin also increased.

Professor Currie said there were several reasons for this increase, including the fact that more people in the Top End had diabetes (a risk factor for the disease) today than in the early 1990s.

He said construction across the Greater Darwin also contributed to higher caseloads, because this work disrupted the soil.

Dr Sarkar-Tyson added that increased awareness likely led to more tests and diagnoses.

A breakdown of today's COVID-19 news in each state and territory

  A breakdown of today's COVID-19 news in each state and territory Saturday saw developments in COVID-19 news around much of the country. Here's a quick guide to what's new.Click on a link below to jump to your state or territory.

Professor Currie said their research provided some evidence that the bacteria can become airborne during a monsoon.

And he warned future caseloads would increase due to climate change.

"Global warming is likely to increase the risk of melioidosis in the future," he said.

"The bacterium will proliferate more because of a combination of things: the warmer temperatures, the greater humidity in the tropics and more increased rainfall."

A warning to others

Professor Currie said people who had underlying health conditions or who drank heavily were most at risk of severe melioidosis.

But Mr Creek, who was not a heavy drinker and had no existing health issues, is using his story to warn others about the seriousness of the illness.

He spent three weeks in hospital and then three months receiving treatment at home post-diagnosis.

"I was probably in a small percentage of people who present with melioidosis that didn't have any obvious pre-existing conditions," Mr Creek said.

Today, more than four years later, Mr Creek has finally fully recovered from the disease.

But his journey back to health has been rocky.

"Six to nine months after the treatment, I started to get really strong muscle pains and aches to the point where I couldn't bend over, I couldn't lift my arms," Mr Creek.

"The fatigue and muscle soreness, I felt afterwards for some two and a half years."

To avoid melioidosis, people in the Top End should wear covered, waterproof footwear while outdoors near mud or soil, put on gloves for gardening and stay indoors during heavy rain and wind.

Trend: Celebs rocking Vera Wang wedding gowns .
Trend: Celebs rocking Vera Wang wedding gownsThe fashion designer sure has been busy this July - both Insecure actress Issa Rae and singer Gwen Stefani got married this month wearing custom Vera Wang gowns, with them both tapping her to create looks for the wedding ceremony and reception.

usr: 5
This is interesting!