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Offbeat New study: How the bowel influences sleep

13:25  01 october  2020
13:25  01 october  2020 Source:   fitforfun.de

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New advances in understanding the interaction of these rhythms and sleep provide the prospect of evaluating their role in normal physiology and the link of Disruption of sleep and circadian rhythms may increase vulnerability to digestive disorders, including reflux, ulcers, inflammatory bowel issues

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Stress , poor nutrition, an unstoppable flow of thoughts: all of these can disrupt sleep .

Much more serious - and not only detrimental to recovery, but also to general health - is what is known as obstructive sleep apnea. These are pauses in breathing during sleep.

Many people suffer from it and are often not even aware of it. But what does the intestine have to do with the disease?

Poorly recovered due to an unnoticed sleep disorder

The diagnosis of obstructive sleep apnea (OSA for short) can only rarely be made because many of those affected are not even aware of their poor sleep.

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New advances in understanding the interaction of these rhythms and sleep provide the prospect of evaluating Abstract: Circadian rhythms and sleep influence a variety of physiological functions Yet the gut has a significant reserve to compensate even after resection of large sections of the bowel .

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In the case of sleep apnea, you wake up repeatedly without noticing it and therefore never fully enter the deep sleep phase.

is to blame for slack muscles in the upper airways, which leads to shallow breathing and repeated cessation of breathing.

The resulting lack of oxygen causes the person affected to wake up briefly again and again.

Poor recovery, exhaustion and tiredness - although you think you have slept through the night - are the result.

Sleep research in mice brings new insights

A research team from Missouri used an study on mice to determine that the intestines are linked to poor sleep caused by this clinical picture.

For this purpose, the sleep behavior of two groups of mice was evaluated for six weeks.

The intervention group was subjected to a lack of oxygen at intervals, which was intended to mimic sleep apnea. The control group could breathe normally all the time.

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Subsequently, intestinal bacteria of the two groups mentioned were transplanted into a third group of mice; one half received bacteria from the mice suffering from artificial sleep apnea, the other half received those samples from the control group.

Intestinal bacteria influence recovery and sleep behavior

The mice with the intestinal bacteria used in the intervention group (the sleep apnea group) showed symptoms of disturbed sleep in the following three weeks - such as increased tiredness despite longer periods of sleep and more frequent naps during the day - despite you Sleep behavior remained unaffected.

These results lead the researchers to conclude that gut health has an impact on sleep.

"For example, if we combine continuous positive airway pressure (CPAP) with bespoke probiotics that alter the patient's gut microbiome," says lead researcher David Gozal to 'Mindbodygreen' , "we may be able to eliminate some of the tiredness and fatigue reduce the likelihood of associated concomitant diseases such as cardiovascular disease or metabolic diseases. "

That this also applies to the human organism has to be proven in follow-up studies.

Provided that this is the case, appropriate treatment options for obstructive sleep apnea with artificially administered intestinal bacteria can be derived from this.

sources

Badran, M. et al. (2020): Fecal microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits sleep disturbances in naïve mice, accessed on September 30, 2020, https://www.sciencedirect.com/science/article/abs/pii/S0014488620302703?via%3Dihub

Ulm University Hospital: Obstructive sleep apnea, accessed on September 30, 2020, https://www.uniklinik-ulm.de/hals-nasen-und-ohrenheilkunde/schlafmedizin/obstruktives-schlafapnoesyndrom.html

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usr: 1
This is interesting!