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Sport The Institut Pasteur de Lille is betting on an old suppo

23:25  20 october  2020
23:25  20 october  2020 Source:   ouest-france.fr

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L’Institut Pasteur de Lille aurait découvert qu’une molécule, le clofoctol, serait efficace contre le Covid-19. © LAMIOT, CC-BY-SA 3.0 The Institut Pasteur de Lille has discovered that a molecule, clofoctol, is effective against Covid-19.

The Institute's mystery anti-Covid molecule is believed to be an old antibiotic. No evidence of effectiveness has yet been published.

The mysterious " particularly effective molecule" against infection by the Sars-Cov2 virus identified by the Institut Pasteur in Lille is believed to be clofoctol. The specialized agency AEF Info released the name last week. Indirect confirmations were collected by Le Figaro. The Institute will not make "no comments" .

At the end of September, the secret announcement of the Institute had aroused some excitement in the media and a certain annoyance in the scientific community.

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In vitro tests

Benoit Déprez, scientific director of Pasteur Lille, justified the secrecy by 's desire "not to arouse hysteria". A shortage of the product would prevent a clinical trial from being carried out, explained the biochemist, also founder of the start-up which had massively screened old drugs. At the same time, an appeal for funds of 5 million euros was launched. A few days later, the luxury group LVMH donated the sum.

Many researchers had deplored the method, both the secrecy and early triumphalism, stressing that the success of in vitro tests (in test tubes) are too often denied thereafter.

Preclinical study

In its usual use, clofoctol targets bacteria that infect the respiratory tract. Sold under the name Octofene, this antibiotic suppository was withdrawn from the French market in 2005 for lack of efficacy. It is still distributed, notably in Italy under the name Gramplus.

A preclinical study on macaques has started, before trials in humans "planned for the end of the year" . No data has yet been released. It is far too early to celebrate.

Lille stumbles on Nice / Ligue 1 (J8) .
OGC Nice ended the LOSC series by scoring a point this Sunday after an undecided match (1-1). © Supplied by Football 365 Dante (OGC Nice) - Jonathan Ikone (Lille) After their various fortunes in the Europa League this week, Nice and Lille met this Sunday at the Allianz Riviera. The LOSC had the opportunity to recover its leader's chair in case of success, but Christophe Galtier's men missed the boat , despite some strong times. A LOSC with reaction The first period was quite contrasted.

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