Tech & Science Primordial 'Asgard' Lifeform Has Been Successfully Grown in The Lab

08:40  17 january  2020
08:40  17 january  2020 Source:   sciencealert.com

New Zealand's first Bachelor Art Green will host The Bachelorette NZ this year and insists Dr Lesina Nakhid-Schuster is 'the perfect fit for the show'

  New Zealand's first Bachelor Art Green will host The Bachelorette NZ this year and insists Dr Lesina Nakhid-Schuster is 'the perfect fit for the show' New Zealand's first Bachelor Art Green will be hosting the country's first-ever season of The Bachelorette this year. The 31-year-old is set to guide doctor and occasional actress Lesina Nakhid-Schuste on her search for love.Speaking to Stuff.co.nz on Sunday, he said: 'I got contacted by a producer in the first half of [last] year who said they wanted to put me forward to host a TV show.

An almost fully- formed human brain has been grown in a lab for the first time, claim scientists from Ohio State University. The team behind the Anand claims to have created the brain by converting adult skin cells into pluripotent cells: stem cells that can be programmed to become any tissue in the

Scientists have grown a kidney in a laboratory and shown that it works when implanted into a living animal. In the latest work, Harald Ott of Massachusetts General hospital led a team of scientists who grew a kidney by using an experimental technique that has previously been used to create working

a close up of text on a black background© Imachi et al., bioRxiv, 2019

When scientists ran DNA analysis on a sediment core taken from the floor of the Arctic ocean back in 2010, they found something surprising. A previously unknown organism belonging to the strange domain of microbes called Archaea appeared to have genomic characteristics associated with a totally different domain - Eukaryota.

They named their discovery Lokiarchaeota, after the Loki's Castle hydrothermal vent near Greenland where it was found; but doubt shadowed the finding. Could the sample have been contaminated by something else in the core?

Now, thanks to the work of Japanese scientists, those doubts can be put to rest. For the first time, they have isolated Lokiarchaeota, and grown it in a lab.

Flat ASX open tipped amid US, Iran tension

  Flat ASX open tipped amid US, Iran tension US investors remain concerned about tensions between the US and Iran, which could see the ASX edge lower once trading opens.The SPI200 futures contract was up three points, or 0.04 per cent, to 6767.0 at 0800 AEDT on Wednesday, after losses of almost two per cent for oil majors Exxon Mobil Corp and Chevron Corp kept the blue-chip Dow Jones Industrial Average in the red.

Lab - grown beef is very likely to have a much smaller environmental footprint than intensively reared beef. But Marco Springmann, at the University of Other companies pursuing lab -based meat include Mosa Meats in the Netherlands, set up by Prof Mark Post, who produced the original lab burger in

After 15 years of trying, scientists successfully transplanted lab - grown lungs into pigs. To overcome these challenges, internist Joan Nichols and her colleagues at the University of Texas Medical Branch have spent years finding ways to engineer a lung from scratch in the laboratory , using donated cells.

That means, for the first time, researchers can closely study and interact with living Lokiarchaeota, which could help us to find our very first ancestors on this incredible blue planet. Their research was released last year and has now been published in the journal Nature.

The tree of life, at its base, is divided into three domains. One of those is occupied by bacteria - single-celled microbes that don't have a nucleus or membrane-bound organelles, and get around by waving hair-like structures called flagella. Another is eukaryotes, organisms whose cells have nuclei and membranes. That domain includes us humans, animals, plants, and algae.

And then there are archaea. These are a lot like bacteria, in that they lack nuclei and membrane-bound organelles, and get around using flagella. But there are a few key differences. They divide differently. Their cell walls are made of slightly different stuff. And their RNA is different enough to separate them on the phylogenetic tree.

Ellen DeGeneres' houses will have you drooling

  Ellen DeGeneres' houses will have you drooling It's no secret that Ellen DeGeneres is a prolific house flipper, transforming lacklustre properties into envy-inducing luxury homes and usually selling them on for big profits. Let's take a look back through her illustrious property journey

University of Texas scientists transplant lab - grown lungs into pigs without triggering an immune reaction, moving us closer to bioengineered 1 in the journal Science Translational Medicine, each pig continued to breathe using its own right lung, its left lung having been replaced by a lab - grown one.

Lab - grown organ transplants aren't right around the corner, but they may There's still a while to go before human transplants are an option. In addition to the question of functionality, long-term viability Even so, the research group believes it could grow human-ready lungs in the next five to 10 years.

But then along came Lokiarchaeota - followed by other archaea specimens that had eukaryotic characteristics. These were named Thorarchaeota, Odinarchaeota and Heimdallarchaeota (to follow the same naming convention).

Collectively, they are called the Asgard archaea, and some scientists think they could be the origin of eukaryotic life - perhaps after an Asgard-like archaeon swallowed up a bacterium.

But it's hard to tell without studying the organisms in isolated detail. This is where the Japanese scientists come in. They retrieved a sediment core from the seabed in the Nankai Trough, 2,533 metres (8,310 feet) below sea level, in 2006.

This was before anyone knew about Asgard archaea. Only later, an RNA analysis of their rich sample revealed the presence of a Lokiarchaeota-like organism.

When the team started their work, they didn't know this yet. They carefully cultivated their samples for five years, in a methane-fed continuous-flow bioreactor system designed to mimic the conditions of a deep-sea methane vent. Very slowly, the microbes multiplied.

Made Entirely From Cells, These Adorable 'Xenobots' Are Practically Alive

  Made Entirely From Cells, These Adorable 'Xenobots' Are Practically Alive With the help of a supercomputer, scientists have built tiny machines comprised entirely made of biological materials. Able to survive for days and even weeks, these xenobots could eventually be used to deliver drugs inside the body and to clean up the environment. New research published in Proceedings of the National Academy of Sciences describes the xenobot—a “reconfigurable organism” designed by a collaborative team from Tufts University, the University of Vermont, and the Wyss Institute at Harvard. require(["inlineoutstreamAd", "c.

Scientists have successfully implanted vaginas grown in laboratories into four teenage girls who have a congenital condition which meant their own did not "This pilot study is the first to demonstrate that vaginal organs can be constructed in the lab and used successfully in humans," said lead

Pigs implanted with lab - grown lungs recovered from surgery with no breathing problems. CUSTOM-MADE Pigs implanted with bioengineered lungs (like the one growing inside the bioreactor tank above) showed no signs of rejection after the This article is only available to Science News subscribers.

The next step was to place samples from the bioreactor in glass tubes with nutrients to keep them fed and growing. There they sat for another year, finally starting to develop a very faint population of Lokiarchaeota.

Then, the team invested even more time into isolating, cultivating and growing this slow-dividing population. Common bacteiral populations usually take about half an hour to double. Lokiarchaeota took 20 days.

"Repeated subcultures ... gradually enriched the archaeon with extremely slow growth rate and low cell yield," the researchers wrote in their paper.

"The culture consistently had 30-60 days of lag phase and required over 3 months to reach full growth [..] Variation of cultivation temperatures, and substrate combinations and concentrations did not significantly improve the lag phase, growth rate or cell yield."

In all, the experiment took 12 years. The researchers named their cultivated microbe Prometheoarchaeum syntrophicum - after Prometheus, the ancient Greek mythological Titan who was credited with creating humans out of clay.

Margot Robbie feels like an adult now

  Margot Robbie feels like an adult now Margot Robie left home when she was 17 but didn't truly feel like an adult until she'd learned to say no.The 29-year-old actress was just 17 when she left home for a role in soap 'Neighbours' but the 'Birds of Prey' star - who is married to Tom Ackerley - just felt like a "kid trying to do grown-up things" at the time and only feels like she's matured now she's able to take control of her life.

Lab - grown lungs have been successfully placed in pigs for the first time. How long until we get to humans? This becomes even trickier in the case of lungs. Uniquely among organ donation, in cases where the donor's lung is not the proper size for the recipient, an adjustment must be made to make it

human lungs in a lab have now performed multiple successful transplants in pigs. armature to lend his creation form , Nichols' team grew the tissues and blood vessels of their lab - grown lungs atop a The lung was positioned so Nichols and her team could monitor the placement of catheters in the

They made several curious findings. The first is that Prometheoarchaeum would only grow in the presence of one or two other microbes, the archaeon Methanogenium and the bacterium Halodesulfovibrio. When Prometheoarchaeum breaks down amino acids into food, it produces hydrogen, which the other microbes eat.

If the hydrogen was allowed to hang around, the experiments revealed, this could further hinder Prometheoarchaeum's already slow growth, indicating the archaea has a symbiotic relationship with other microbes, in this case syntrophic - meaning the growth of one species or both depends on what the other eats.

Then, when the organism was examined under an electron microscope, it revealed an unusual shape for an archaeon - long tentacles sprouting from its body, within which its partner microbes nestled. When oxygen started increasing on Earth, the researchers hypothesised, this organism could have switched to a relationship with bacteria that used oxygen, increasing its chances of survival, and setting out on the path to eukaryotic life.

And indeed, DNA sequencing revealed the eukaryotic characteristics seen in other Asgard archaea.

Obviously more work needs to be done. Prometheoarchaeum might be quite different from the archaea of billions of years ago. And it's far from definitive proof that eukaryotes evolved from archaea.

The study is so far available ahead of peer-review, so it will be interesting to see what the scientific community makes of it, in time. But no matter what happens now, we're going to learn a heck of a lot from this work.

"This is a monumental paper that reflects a tremendous amount of work and perseverance," evolutionary microbiologist Thijs Ettema of Wageningen University, who wasn't associated with the paper, told Nature back in August 2019, when the work was first announced.

"It's a major step forward in understanding this important lineage."

The research has been published in Nature.

A version of this article was first published in August 2019 when the research was released ahead of peer review in the preprint journal bioRxiv.

Did asteroid that hit Australia help thaw ancient 'snowball Earth'? .
Did asteroid that hit Australia help thaw ancient 'snowball Earth'?WASHINGTON (Reuters) - Scientists have identified Earth's oldest-known impact crater, and in doing so may have solved a mystery about how our planet emerged from one of its most dire periods.

—   Share news in the SOC. Networks
usr: 13
This is interesting!