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World Exclusive: Study suggests dengue may provide some immunity against COVID-19

22:20  22 september  2020
22:20  22 september  2020 Source:   reuters.com

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A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against COVID - 19 .

A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against COVID - 19 .

a man in a blue shirt: The coronavirus disease (COVID-19) outbreak in Oldham © Reuters/PHIL NOBLE The coronavirus disease (COVID-19) outbreak in Oldham

By Pedro Fonseca

RIO DE JANEIRO (Reuters) - A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against COVID-19.

a close up of a map: The inverse exponential correlation between COVID-19 case incidence as a function of the dengue fever incidence for a sample of countries in Latin America, Asia, and a few islands in the Pacific and Indian Oceans is seen in this undated handout image © Reuters/UFPB The inverse exponential correlation between COVID-19 case incidence as a function of the dengue fever incidence for a sample of countries in Latin America, Asia, and a few islands in the Pacific and Indian Oceans is seen in this undated handout image

The not yet published study led by Miguel Nicolelis, a professor at Duke University, and shared exclusively with Reuters, compared the geographic distribution of coronavirus cases with the spread of dengue in 2019 and 2020.

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A new study that analysed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against Covid - 19 .

RIO DE JANEIRO (Reuters) – A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against COVID - 19 .

Places with lower coronavirus infection rates and slower case growth were locations that had suffered intense dengue outbreaks this year or last, Nicolelis found.

"This striking finding raises the intriguing possibility of an immunological cross-reactivity between dengue's Flavivirus serotypes and SARS-CoV-2," the study said, referring to dengue virus antibodies and the novel coronavirus.

a close up of a map: The inverse exponential correlations between COVID-19 case incidences per 100 thousand inhabitants is seen in this undated handout image © Reuters/UFPB The inverse exponential correlations between COVID-19 case incidences per 100 thousand inhabitants is seen in this undated handout image

"If proven correct, this hypothesis could mean that dengue infection or immunization with an efficacious and safe dengue vaccine could produce some level of immunological protection" against the coronavirus, it added.

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A new study that analysed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against Covid - 19 . The not yet published study led by

A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past epidemics of dengue fever that suggests exposure to the mosquito-transmitted illness might provide some level of immunity against Covid -.

a screenshot of a cell phone: The comparison between the geographic distribution of COVID-19 and dengue fever cases is seen in this undated handout image © Reuters/UFPB The comparison between the geographic distribution of COVID-19 and dengue fever cases is seen in this undated handout image

Nicolelis told Reuters the results are particularly interesting because previous studies have shown that people with dengue antibodies in their blood can test falsely positive for COVID-19 antibodies even if they have never been infected by the coronavirus.

"This indicates that there is an immunological interaction between two viruses that nobody could have expected, because the two viruses are from completely different families," Nicolelis said, adding that further studies are needed to prove the connection.

The study was being published ahead of peer review on the MedRxiv preprint server and will be submitted to a scientific journal.

It highlights a significant correlation between lower incidence, mortality and growth rate of COVID-19 in populations in Brazil where the levels of antibodies to dengue were higher.

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[RIO DE JANEIRO] A new study that analysed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever that suggests exposure to the mosquito-transmitted illness may provide some level of immunity against Covid - 19 .

A new study that analyzed the coronavirus outbreak in Brazil has found a link between the spread of the virus and past outbreaks of dengue fever, suggesting exposure to the mosquito-transmitted illness may provide some level of immunity against COVID - 19 .

Brazil has the world's third highest total of COVID-19 infections with more than 4.4 million cases - behind only the United States and India.

In states such as Paraná, Santa Catarina, Rio Grande do Sul, Mato Grosso do Sul and Minas Gerais, with a high incidence of dengue last year and early this year, COVID-19 took much longer to reach a level of high community transmission compared to states such as Amapá, Maranhão and Pará that had fewer dengue cases.

The representation of all COVID-19 © Reuters/UFPB The representation of all COVID-19 "boomerangs" that occurred around major Brazilian state capitals and mid-size cities across the whole country and the lethality and hospitalization data are seen in this undated handout image

The team found a similar relationship between dengue outbreaks and a slower spread of COVID-19 in other parts of Latin America, as well as Asia and islands in the Pacific and Indian Oceans.

a screenshot of a cell phone: Graphs show the individual contribution of the Brazil's 17 state capital cities that were responsible for 98 percent of spreading of COVID-19 cases for the 5570 Brazilian municipalities, from March 1st to June 11th in this undated handout image © Reuters/UFPB Graphs show the individual contribution of the Brazil's 17 state capital cities that were responsible for 98 percent of spreading of COVID-19 cases for the 5570 Brazilian municipalities, from March 1st to June 11th in this undated handout image

Nicolelis said his team came across the dengue discovery by accident, during a study focused on how COVID-19 had spread through Brazil, in which they found that highways played a major role in the distribution of cases across the country.

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the COVID - 19 response.1 Some governments have suggested that the detection of antibodies to the SARS-CoV-2, the virus that causes COVID - 19 , could serve as the The measurement of antibodies specific to COVID - 19 . The development of immunity to a pathogen through natural infection is a

The studies suggesting one can't become reinfected with the coronavirus were both published in the journal Science on Wednesday. In one of the studies He added, “It has long been suspected that there would be natural protective immunity [after recovery from COVID - 19 ] because most viruses do

The distribution of ICU beds across all Brazil, and the superimposition of the COVID-19 death distribution (color code legend on the left lower corner) on top of the ICU bed distribution are seen in this undated handout image © Reuters/UFPB The distribution of ICU beds across all Brazil, and the superimposition of the COVID-19 death distribution (color code legend on the left lower corner) on top of the ICU bed distribution are seen in this undated handout image

After identifying certain case-free spots on the map, the team went in search of possible explanations. A breakthrough came when the team compared the spread of dengue with that of the coronavirus.

"It was a shock. It was a total accident," Nicolelis said. "In science, that happens, you're shooting at one thing and you hit a target that you never imagined you would hit."

(Reporting by Pedro Fonseca; writing by Stephen Eisenhammer; Editing by Bill Berkrot)

a screenshot of a cell phone: Maps of Brazil representing the routes of the main federal highways, geographic distribution of COVID-19 cases on three dates and the distribution of COVID-19 deaths on August 1st are seen in this undated handout image © Reuters/UFPB Maps of Brazil representing the routes of the main federal highways, geographic distribution of COVID-19 cases on three dates and the distribution of COVID-19 deaths on August 1st are seen in this undated handout image

This Brave Scientist Deliberately Feeds Himself to Infected Mosquitoes For Science .
It started with an arm covered in mosquitoes. But this wasn't just your unlucky friend at a summer barbecue. Perran Ross's arm was lunch for a swarm of mosquitoes infected with a bacterium called Wolbachia – part of a sweeping and ambitious strategy to rid the world of dengue fever. Those that have experienced dengue fever aren't likely to forget it. The dengue virus passes between humans via mosquitoes, with those infected suffering headaches, vomiting, muscle pains, skin rash, and a characteristic high fever for days on end.

usr: 0
This is interesting!