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World sensation! Doctors transplant Schweinherz successfully a man (57) - with video

13:36  11 january  2022
13:36  11 january  2022 Source:   berliner-kurier.de

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what a sensation in the USA. For the first time, doctors have succeeded in transplanting a man's heart of an extra-breeded pig. It could be a groundbreaking progress in medicine. Because at present, not all people who stand on the transplant list can be actually saved.

  Sensation! Ärzte transplantieren Schweineherz erfolgreich einem Mann (57) – mit VIDEO © Provided by Berliner Kurier

"This organ transplant has shown for the first time that the heart of a genetically modified animal can work without immediate repulsion by the body like a human heart," explained the Medical Faculty of the University of the State of Maryland on Monday. The 57-year-old patient, David Bennett, go well three days after transplantation.

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"I had the choice to die or to take this transplant," he says now. "I want to live. I know it's a shot into the blue, but it's my last choice. "The US pharmaceutical authority FDA had given an emergency approval for the procedure. David Bennett, who had spent the last few months bedridden on a heart lung machine, added, "I am looking forward to being able to leave the bed after my recovery."

The patient suffered from a heart disease in the final stage. The transplantation of pork hearts was the "only" treatment option, explained the University of Maryland. Because the man had not been admitted to a conventional organ transplant.

"That was a groundbreaking operation that brings us a step closer to solve the crisis of the organism," explained the surgeon Bartley Griffith, who had used the pork heart. "We want to go cautiously. But we are also optimistic that this world's first operation will give patients in the future an important new option. "

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the pig, from which the heart originated, had been genetically changed to eliminate a certain sugar. Otherwise, this sugar would have triggered a strong immune response of the patient, which had led to a rejection of the organ. Even a gene that had led to excessive growth of pork heart tissue was "switched off". In total, four paved areas were eliminated and six human genes are inserted into the genome of the pig to prevent rejection of the heart by Bennett's body.

For the gene changes, the Biotech company Revivicor resident in the US state of Virginia is responsible. This had already supplied the pig, which was used in a groundbreaking kidney transplantation on a brain-dead patient in October in New York.

However, while this preceding procedure was only an experiment for testing the concept and the kidney was connected outside the body to the blood circulation of the patient, the new intervention will rescue further lives in the future. The scientists had kept the animal organ before implantation in a preserving machine. The intervention also used the physicians a novel experimental drug to suppress immune defense.

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alone in the US alone, around 110,000 people are currently waiting for a donor body. According to official numbers, more than 6,000 people die year before a transplant could be made.

Because of the lack of human donor organs, research relies great hope into the so-called xenotransplantation - the transplant of animal organs. Supplant already heart valves of pigs and pig trains in combustion victims. Pigs are considered ideal donors due to their size, rapid growth and good breeding properties. In addition, they are socially accepted as donor animals rather, as they are already slaughtered for food purposes.

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