Health Graying Hair Linked To Immune Response, Study Finds

11:31  07 may  2018
11:31  07 may  2018 Source:   medicaldaily.com

This Is What Fast Food Actually Does to Your Immune System

  This Is What Fast Food Actually Does to Your Immune System ***ImagePlaceholder*** http://www.besthealthmag.ca/wp-content/uploads/2018/02/Fast-food-burger-chicken-nuggets-pop.jpg photo credit: shutterstock Don’t get enough sleep? Booze too much? Stressing out? These everyday habits could be ruining your immune system, but the worst culprit may be your fast food habit. A recent study out of the University of Bonn suggests that a typical 'Western diet' (a lot of red meat, sugar, and saturated fat and not much fiber -- basically synonymous with fast food) can kick the immune system into overdrive, causing inflammation. The study, published in the journal, Cell, goes on to connect that inflammatory response to serious conditions like cardiovascular diseases (read: stroke or heart attack) and type 2 diabetes, which itself can lead to cardiovascular diseases, as reported by Science Daily. Researchers, led by Eicke Latz, MD, PhD, director of the Institute for Innate Immunity of the University of Bonn in Germany, placed mice on a Western diet and observed that after only one month, the mice had an inflammatory response akin to that triggered by a serious bacterial infection. 'Fast food thus causes the body to quickly recruit a huge and powerful army,' noted the University of Bonn's press release, as that process notably increases the immune cells in the mice's blood. Even worse? The immune response isn't reversible, the scientists discovered.

Gray Hair© Gray Hair Gray Hair

What is the science behind our hair turning gray? Researchers from the University of Alabama at Birmingham have a possible answer and it may also explain why vitiligo patients develop unpigmented patches of skin.

The study titled "A direct link between MITF, innate immunity, and hair graying" was published in the journal PLOS Biology on May 3.

"My lab harnesses the power of mouse models of hair graying to better understand stem cells and aging. The stem cells we study are the melanocyte stem cells in the hair follicle, which are the stem cells that are essential for producing melanocytes," explained lead study author Melissa Harris, an assistant professor of biology at the University of Alabama.

Study Finds This Very Common Morning Drink Linked To Skin Cancer

  Study Finds This Very Common Morning Drink Linked To Skin Cancer Before you head to the kitchen for that big glass of OJ, take a look at this recent shocking study. I'm sad to say that this news will not brighten your day. Researchers from Brown University's Warren Alpert Medical School say that a study from the Journal of Clinical Oncology, which they recently conducted, shows that drinking citrus juices, like orange juice, may increase your risk of developing the most deadly form of skin cancer.I know; I'm upset about this, too. Turns out, the sweet glass of orange juice Mom gives you every morning isn't as healthy as you thought.

Melanocytes are pigment-producing cells responsible for giving your hair its natural color, be it blonde, brown, red or black. But when melanocytes suffer damage as a response to natural aging or a serious illness, the newly grown hair ceases to carry its natural pigment. This is how people develop gray or white hair.

Previously, the research team had found that a protein called MITF (melanogenesis-associated transcription factor) controlled the genes to create hair color pigment. The team examined mice that were bred to develop premature gray hair and found an excessive production of MITF. However, even when they bred mice to produce the protein at lower levels, their fur continued to turn prematurely gray at a similar pace as before.

Always Sick? Here's Why More Exercise May Be the Best Preventative Medicine

  Always Sick? Here's Why More Exercise May Be the Best Preventative Medicine Always Sick? Here's Why More Exercise May Be the Best Preventative MedicineThe long-standing myth that strenuous exercise can weaken the immune system has finally been debunked. According to Dr. Natasha Bhuyan, an MD at One Medical, this popular misconception was rooted in the belief that vigorous physical activity would cause immune cells to deplete. Back in the '80s, research found that marathon runners had higher rates of colds than the rest of us - but these dated scientific studies don't stand up to today's scientific methods. Researchers are now saying that those marathon runners likely had post-run throat irritation or allergies, not colds.

The new research found that MITF may actually turn off genes for an anti-virus, immune protein called interferon. When the researchers triggered an anti-virus response in the mice, it was found that the mice having low levels of this protein ended up losing melanocytes and developing gray fur.

Since this was a mouse study, it remained unclear how far this mechanism could work in the case of human beings. But Harris pointed that it may be one of the possible reasons why some people suddenly develop gray hair in their youth. "Perhaps, in an individual who is healthy yet predisposed for gray hair, getting an everyday viral infection is just enough to cause the decline of their melanocytes and melanocyte stem cells leading to premature gray hair," she said.

Another significant takeaway from this discovered mechanism is that it may also explain disruptions in skin pigmentation in addition to affecting hair pigmentation.

This Vitamin Supplement Can Help Prevent Rheumatoid Arthritis, New Study Shows

  This Vitamin Supplement Can Help Prevent Rheumatoid Arthritis, New Study Shows Read on to discover which vitamin you may want to start including in your daily routine.Vitamin D is considered an essential part of healthy living. From reducing the risk of asthma attacks, treating sunburns and even lessening the symptoms of depression, vitamin D is frequently supported by medical experts for its many benefits. Based on the findings of a new study, there’s one more reason you may want to check in with your healthcare provider about your vitamin D levels.

"These results may enhance our understanding of hair graying. More importantly, discovering this connection will help us understand pigmentation diseases with innate immune system involvement like vitiligo," added co-author William Pavan, chief of the Genetic Disease Research Branch at the National Institutes of Health (NIH).

Vitiligo is a condition that leads to the loss of natural skin color, typically in patches, as cells lose the ability to produce melanin. It affects somewhere between 0.5% to 1% of the human population.

Related video: Scientist Find Cells Linked To Graying Thinning Hair (Provided by Wochit News)

Experimental Drug Could Reverse Damage Caused By Western Diet .
While further research is needed, the compound showed potential to help create medication that could speed up wound healing and reverse balding.The study, funded by the National Institutes of Health, was published in the journal Scientific Reports on July 30.

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