•   
  •   
  •   

Canada ‘World first’ Parkinson’s treatment undergoing clinical trial in Toronto

07:15  30 october  2020
07:15  30 october  2020 Source:   globalnews.ca

Phoenix Rising FC relinquishes hosting rights for 2020 USL Championship Final after earning home-field in part due to forfeit

  Phoenix Rising FC relinquishes hosting rights for 2020 USL Championship Final after earning home-field in part due to forfeit Phoenix Rising relinquished claim to home-field advantage for the 2020 USL Championship Final out of respect to the LGBTQ community.Having tied Louisville City FC in total points and victories thanks to a forfeit by San Diego Loyal, Phoenix Rising had earned hosting priority based on a third tiebreaker: goal differential. But because that forfeit was the result of San Diego's protest of an alleged homophobic slur by Phoenix forward Junior Flemmings, Rising management recognized what might have been a glaring optics issue.

Phase I trial : researchers test a new drug or treatment in people for the first time. A small group of people, typically fewer than 100, are monitored to evaluate the drug or treatment ' s ClinicalTrials .gov is a registry and database of publicly and privately support clinical studies conducted around the world .

Parkinson ' s clinical trials are the best way to find out whether a new treatment is safe, effective and beneficial to people with Clinical trials can help people with Parkinson ’ s in many ways. Some of the benefits include All medications must undergo rigorous testing before they can be approved for use.

Researchers in Toronto are in the early stages of developing what’s being called a "world-first" treatment for Parkinson’s disease.

a man standing in front of a curtain: Sunnybrook's Dr. Nir Lipsman is co-leading a study with Dr. Lorraine Kalia and Dr. Suneil Kalia of University Health Network on a new treatment for Parkinson's © Sunnybrook Health Sciences Centre Sunnybrook's Dr. Nir Lipsman is co-leading a study with Dr. Lorraine Kalia and Dr. Suneil Kalia of University Health Network on a new treatment for Parkinson's

Currently in its first phase of clinical trials, the ultimate goal of the new treatment would be to treat symptoms of Parkinson’s, prevent further decline in patients and reduce the amount of medications that people need to take for the illness, according to Dr. Nir Lipsman, the study’s co-principal investigator and a neurosurgeon at Sunnybrook Health Sciences Centre.

3 Breaking Stocks Still Interesting

 3 Breaking Stocks Still Interesting © Powered by The Motley Fool Motorcycle Stunt If you're a fan of growth investing , you know it makes sense to look for companies that you are right now can buy where they are just starting to break out of the crowd - and then sell when they can no longer achieve good results for shareholders.

MRI-Focused Ultrasound Undergoing Phase 3 Clinical Trial for Parkinson ’ s Treatment . “The goal of the focused ultrasound treatment is to both lessen the main symptoms of Parkinson ’ s disease, which include tremors, rigidity and slow movement, as well as treat the dyskinesia that is a medication

The first cell transplant trial for Parkinson ’ s happened in the 1980s and was followed by the first You can find out more about this and read James’s story about undergoing treatment in our blog We will look at current trials in more detail later, but to understand how they differ let’s first take a

4:06

More Parkinson’s surgeries available, but still not enough

More Parkinson’s surgeries available, but still not enough

“That’s ultimately the goal — to change both the day-to-day activities of patients but also the course of their illness,” he said. “We’re still, again, (in) early days, but this is a critical first step.”

Parkinson's is a neurodegenerative disorder where patients experience tremors, muscle rigidity and have difficulty with balance, among other symptoms.

More than 100,000 people in Canada have been diagnosed, according to Parkinson Canada, and there is no cure.

Read more: Why are my hands shaking? What to know about tremors

The Toronto researchers, who are based at Sunnybrook as well as University Health Network, are using a focused ultrasound technology to deliver a treatment directly to the regions in the brain that are affected by Parkinson’s.

The latest news on COVID-19 developments in Canada

  The latest news on COVID-19 developments in Canada The latest news on COVID-19 developments in Canada (all times Eastern): 2 p.m. Quebec's deputy premier has a dire warning for those living in the provincial capital and the neighbouring Chaudiere-Appalaches region amid a rising number of cases of COVID-19. Genevieve Guilbault says people haven't been following public health guidelines, resulting in a spike of cases in the two regions that could threaten the ability to provide medical treatment if it's not brought under control. Both regions were largely spared during the first wave, but Guilbault says in Chaudiere-Appalaches, there have been four times more cases and five times more deaths this time.

Can this clinical trial give hope to the estimated ten million affected by Parkinson ’ s globally? In the second episode, cameras continue to follow the lives of the The surgery and infusions are medical firsts , offering a whole new way of delivering drugs to the brain. It leads to Pfizer, the world ’s biggest

Can this clinical trial give hope to the estimated 10 million affected by Parkinson ’ s globally? This new trial sees a further 42 volunteers undergo extensive brain surgery and then be randomised to After five years of one of the world ’s most ambitious medical trials , we find out whether the drug is

This is done by non-invasively opening a passage in the blood-brain barrier — the physical obstacle in the body that prevents compounds, including potentially useful therapies, from gaining access to the brain, Lipsman said.

“What an ultrasound allows us to do is create a kind of temporary window in that blood-brain barrier to allow the delivery of therapies to the brain that ordinarily cannot get in,” he added.

“Now what we can do is open the blood-brain barrier entirely non-invasively with the patient in the MRI scanner, so they don’t have to have skin incision or holes in the skull.”

Researchers are looking at whether delivering an enzyme called Glucocerebrosidas to the brain will help prevent the build-up of a protein that is associated with Parkinson's called alpha-synuclein.

4:59

Larry Gifford on living with Parkinson’s

January 2015 attacks: Ali Riza Polat, suspected of having been Amedy Coulibaly's right hand man finally heard

 January 2015 attacks: Ali Riza Polat, suspected of having been Amedy Coulibaly's right hand man finally heard The special assize court which judges the January 2015 attacks chose to hear Ali Riza last Polat, the main accused in this trial because he is the only one to have to answer for "complicity in crime" © Benoit PEYRUCQ / AFP Ali Riza Polat - in the foreground above his lawyer, Me Coutant-Peyre - is the last of the eleven defendants present to be heard on the facts TRIAL - The special assize court which judges the attacks of January 2015 chose to hear last Ali Riza Polat, main defendant in this tr

This pioneering GDNF trial tested whether GDNF treatment can slow, stop or reverse Parkinson ' s - something no current treatment can do. Become a member. World Parkinson ' s Day. Parkinson ' s UK is the operating name of the Parkinson ' s Disease Society of the United Kingdom.

Parkinson ’ s Disease. Toronto ’s 30 Best Doctors: Gynecologist. His clinical trials had anaphylactic patients, both kids and adults, eating increasing doses of peanut flour, then eventually whole peanuts. After completing animal trials , Ryan, in a world first , successfully inserted a coronary

Larry Gifford on living with Parkinson’s

Focus on infrastructure, involve community to fix reserve water issues: observers

  Focus on infrastructure, involve community to fix reserve water issues: observers The evacuation of a remote Ontario First Nation over the latest development in a decades-long water crisis has highlighted the need to focus on reserve water infrastructure systems as a whole and involve community members in managing them, observers say. Training residents to manage First Nation water facilities, ensuring distribution systems function properly, and developing standards for on-reserve water infrastructure are all examples of what can be done to solve the issues such as those experienced by the Neskantaga First Nation, experts and Indigenous officials said.

PATIENTS could be recruited for the first clinical trial of a stem cell treatment for Parkinson ' s disease before the end of next year. Professor Jun Takahashi, a Parkinson ' s neurosurgeon from Kyoto University, said: “This study is our answer to bring iPS cells to clinical settings.

For clinical trials , a planned measurement described in the protocol that is used to determine the effect of an intervention/ treatment on participants. A type of intervention model describing a clinical trial in which two or more groups of participants receive different interventions.

The goal for this phase of the trial is to have six people undergo three rounds of treatment, with follow up for at least six months. Three patients are already signed up.

Pat Wilson, 56, of Cookstown, Ont., is the first person to participate in the study. While she hasn't had improvement so far, she has had to adjust her medication because she's seen a change in how her body reacts to it.

Wilson was diagnosed with Parkinson's in 2013 and her father also had the disease. She wanted to participate in the trial to try to help others.

Read more: When Life Gives You Parkinson’s podcast: More than care givers, we are partners

"It's important because we need better treatments, longer-lasting treatments, maybe. Anything to help people in the future who might get it."

Over time, as the Toronto researchers gain experience and conduct additional trials, Lipsman said they hope they can demonstrate that they’re moving the dial when it comes to preventing neurodegeneration from taking place.

“If we can do that, then we can prevent disability, we can improve quality of life and we can prolong life as well,” he said.

23 male celebrities who have bleached their hair .
Celebrities like Zac Efron, Pharrell Williams, and Justin Timberlake have gone blonde over the years.

usr: 25
This is interesting!