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Canada All-round protection Before all virus variants: US Army tests the super vaccine against Corona!

14:51  12 january  2022
14:51  12 january  2022 Source:   berliner-kurier.de

around CureVac it has become quiet

 around CureVac it has become quiet In the first Corona year, the Tübingen were still at the very beginning in the development of a first vaccine - in the meantime it has become quite quiet about the biotech company Cureevac. © Bernd Weissbrod / DPA Franz-Werner Haas, CEO of CureVac.

creates the US military the decisive step in the fight against the Corona pandemic? A research institute of the US military tests a corona vaccine that should protect against infections with a variety of virus variants. Phase 1 studies in humans have already taken place, it was said from the Walter Reed Army Institute of Research (Wrair).

  Rundumschutz vor sämtlichen Virus-Varianten: US-Armee testet den Super-Impfstoff gegen Corona! © Provided by Berliner Kurier

There, the spike ferritin Nanoparticle (SPFN) Corona vaccine was developed. And a number of recently published preclinical study results shows that the active ingredient not only causes a strong immune response, but may also provide broad protection against worrying SARS COV 2 variants and other coronaviruses.

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of the spike ferritin nanoparticle vaccine, short SPFN, is a protein vaccine. Ferritin is one in man naturally and frequently occurring protein containing iron. It folds from alone to a ball with 24 subunits, where the spike protein is attached to another corona variant. With the help of the spike protein, coronaviruses penetrate into human cells.

, these ferritin nanoparticles are sprayed with the viral eggs and a pricing amplifier, the immune system forms antibodies and T cells against the antigen. The principle is similar to the NovaVax protein vaccine, which will soon be admitted in the EU.

COVID 19 vaccination with ferritin nanoparticles has already been successfully tested on Rhesus monkeys. The vaccine has triggered strong neutralizing antibodies against the original coronavirus as well as the four variants of alpha, beta, gamma and delta and even had to be effective against the SARS-1 virus, although this virus type differs significantly from SARS-COV-2, write The researchers of the WAIR in the trade magazine Science Translational Medicine.

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The analysis of the first tests started in humans will provide information on whether the effectiveness of SPFN can also be transferred to humans and whether the vaccine is compatible.

According to media reports, the laboratory tests have shown that the antibodies caused by the vaccine can also combat the omikron variant.

The agent should be the way "paving for a universal vaccine that does not only protect against the current virus, but also against future variants," said vaccine co-learning Kayvon Modjarrad from the Wrair. "We want to wait for the clinical data before we announce them to the public, but so far everything is exactly how we have hoped for us."

"The accelerated occurrence of human coronaviruses in the last two decades and the increase of SARS-COV -2 variants, including most recently omikron, underline the persistent need for next-generation preventive vaccines that provide broad protection against coronavirus diseases, "continues Modjarrad. "Our strategy was to develop a pan-coronavirus' vaccine technology that could potentially provide safe, effective and permanent protection against multiple coronavirus tribes and species."

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