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Health & Fitness Eureka! The once-a-night pill that can banish snoring

03:25  27 october  2020
03:25  27 october  2020 Source:   dailymail.co.uk

Women on the pill may face high blood clot risks from COVID-19

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The once - a -day pill slashed snoring rates by almost 70 per cent in a small U.S. trial. Hope for millions of couples: A new pill could prevent snoring so everyone can get a good night 's sleep. If so, it may also help to reduce the risks of high blood pressure and heart disease linked with sleep apnoea.

Professor Kevin Morgan offers advice on what insomniacs can do to help get to sleep.

a person sitting on a bed: MailOnline logo © Provided by Daily Mail MailOnline logo

A Pill taken at bedtime could stop snoring for good.

The new tablet eases the symptoms of obstructive sleep apnoea (OSA) — which affects up to two million people in Britain, causing heavy snoring and, sometimes, interrupted breathing.

Initial results from clinical trials suggest the night-time pill may ease these problems by up to 74 per cent.

Both men and women can get OSA, but it is most common in men over the age of 40; obesity is one of the main risk factors. It occurs when the muscles in the airway, which naturally relax as we fall asleep, completely collapse.

The snoring sound is caused by air being forced through a smaller gap in the throat and, when the muscles collapse completely, this can shut off breathing for ten seconds or more.

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Researchers have developed a once - a -month oral contraceptive pill that they say would offer women more choice and control over their fertility. Once swallowed, the pill remains in the stomach for weeks, slowly releasing hormones to prevent a pregnancy. It is specially designed to resist immediate attack

Common complaint: Snorers, and their loved ones, could soon be saved by a pill which if taken daily can cure the sleep disorder. It is the cause of marital strife in the bedroom and many a lost night 's sleep. Now scientists claim that taking a daily pill can curb a common snoring disorder affecting

a man lying on a bed: The new tablet eases the symptoms of obstructive sleep apnoea (OSA) — which affects up to two million people in Britain. Pictured: A man wears a sleep apnoea mask (file photo) © Provided by Daily Mail The new tablet eases the symptoms of obstructive sleep apnoea (OSA) — which affects up to two million people in Britain. Pictured: A man wears a sleep apnoea mask (file photo)

When the brain realises breathing has stopped, it sends out a signal to contract the airway muscles, which normally makes the person wake with a jolt.

In severe cases, sleep can be disturbed every couple of minutes.

Treatments usually include lifestyle changes such as losing weight, cutting down on alcohol, sleeping on your side, and using a continuous positive airway pressure (CPAP) device, a mask worn over the face during sleep that gently forces air into the lungs to stop the airway from collapsing.

However, some people find the mask cumbersome and research suggests nearly a third never use the device, or abandon it. A once-a-day pill is seen by some sleep experts as the Holy Grail of sleep apnoea treatment.

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Everyone snores occasionally. It’s a natural occurrence due to the state your throat moves into during sleep. But if it’s severe, it can disrupt sleep patterns, cause insomnia and lead to irritability. In this episode of Ancient Medicine Today, I share how to stop snoring quickly and naturally, including tips

I tested Nytol One- A - Night and Nytol Original, and discuss the sedative effect, side effects and further information in this review. On the third night, I don’t think the sedative effect was quite as strong. The manufacturer advises that you can develop a tolerance to Nytol, but night 3 seemed quite soon to me.

The new tablet, currently code-named AD109, contains two existing medications.

The first, atomoxetine, has been around for nearly 20 years and is widely used to treat attention deficit hyperactivity disorder (ADHD) in children, by increasing levels of a brain chemical called noradrenaline, which helps to improve concentration.

a person sleeping on a bed: A once-a-day pill is seen by some sleep experts as the Holy Grail of sleep apnoea treatment (file photo) © Provided by Daily Mail A once-a-day pill is seen by some sleep experts as the Holy Grail of sleep apnoea treatment (file photo)

U.S. scientists developing the new pill believe noradrenaline also stimulates the release of cells, called motor neurons, that keep airway muscles in good condition — reducing the risk of them 'collapsing' during sleep.

The other drug, oxybutynin, is usually prescribed to patients with urinary incontinence, stopping embarrassing leaks by reducing spasms in muscles that control the bladder.

In the throat and airway, oxybutynin is thought to act on receptors that make the muscles controlling the tongue contract — effectively holding it in place, rather than blocking the throat and causing snoring.

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Snoring is no respecter of the glamorous. Elizabeth Taylor was a snorer and so is Rihanna, who once snored so loudly during an American Airlines flight Little Snoring is listed in the Domesday Book as Esnaringa, Snaringa and Snarlinga, named after Snare, a local leader, and was gradually corrupted

Sometimes, what sounds like snoring is just how they breathe as a newborn. As they grow, a newborn’s breathing typically gets quieter. However, if your baby starts snoring , and has other symptoms, you’ll want to make sure that those noises aren’t an indication of something more serious.

Neither of these drugs is currently used to treat OSA, but a 2018 study, by Brigham and Women's Hospital in Boston, U.S., in which the two drugs were given at the same time to 20 snorers, revealed a powerful effect after just one night.

Some patients went from suffering an average of nearly 30 breathing interruptions an hour to just seven — a drop of 74 per cent – with symptoms improving from the first night in some cases.

Patients' blood oxygen levels — important for heart and brain function — also increased significantly as they were able to get more air into their lungs.

Now a U.S. firm, called Apnimed, has combined these two medicines into one capsule and is setting up a clinical trial.

However, the treatment may not be without risks. Oxybutynin can cause dry eyes, stomach cramps and drowsiness; while atomoxetine has been linked with depression and suicidal thoughts in some children given it for ADHD.

Dr Neil Stanley, an independent sleep expert and a member of the British Sleep Society, says: 'These are interesting preliminary findings and the reduction in symptoms is very promising.

According to trichologists, this is how nix a dry scalp for good

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The night before Jane lay awake. She had (1) . preparing for the next day (2) a long time and now she couldn't sleep. Her team (3) playing the local champions at water polo in the final and Jane was the captain.

Start with five minutes once a day, but if you are in pain and have been for a long time, or are feeling very tense and stressed, aim to build to 30 minutes twice a day. Regular practising will enable your nervous system to 'rewire' itself and, while you are doing this, active healing will be going on.

'But more research is needed to see if the effect is sustained.'

Why you might get more tummy troubles in winter

Stomach aches appear to peak in winter, according to a study in the journal Therapeutic Advances in Gastroenterology.

Researchers from the Poznan University of Medical Sciences in Poland analysed more than 24 million Google searches made over four years and found that enquiries about abdominal pain and related conditions such as vomiting increased by around 30 per cent in winter compared to summer.

Heavier meals and spending more time on the internet during the winter months may partly explain the rise.

Eating seaweed weekly might reduce the risk of non-alcoholic fatty liver disease (NAFLD) by almost 20 per cent, according to a study by Tianjin Medical University in China.


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Anti-inflammatory chemicals in seaweed may ward off the disease, in which severe inflammaton can lead to liver cancer.

Yes, DIY masks made from cloth will protect you!

Homemade face masks are effective at blocking droplets that may carry the Covid-19 virus, according to a new study by the University of Illinois.

Researchers tested 11 common household fabrics used to make masks, such as bed sheets and dishcloths, and compared their breathability and ability to block droplets with medical masks.

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Writing in the journal Extreme Mechanics Letters, they found that the materials were all effective at blocking 100nm-sized particles — the size of a coronavirus particle — carried by high-velocity droplets similar to those released by speaking, coughing and sneezing.

New way to speed up metabolism

Could scientists have found the secret to speeding up metabolism? Research published in the journal Cell Metabolism has revealed a new way to activate brown fat — a type of body fat which burns energy.

This fat is normally activated by either cold temperatures or chemical signals sent from the brain. Researchers from the University of Sherbrooke in Canada discovered it contains proteins called beta 2-adrenergic receptors, which stimulate the burning process.

They will now use a drug to find out if turning on these proteins could help boost people’s metabolism.

'Vaccine' for cancer could be on the horizon

A new cancer vaccine is showing promise. Tests on animals reveal the immune system is able to successfully identify tumours after the CLEC9A-WT1 jab is given.

The vaccine, which contains antibodies mixed with a protein specific to tumours, revs up the body’s immune response, allowing it to recognise cancer cells and destroy them. It may work on a range of cancers, including breast and pancreatic, the journal Clinical and Translational Immunology reports.

Finger length link with dementia risk

Finger size offers a clue to a woman’s risk of Alzheimer’s disease, according to research by the University of Southern California. Generally, men have shorter index fingers than ring fingers, while women’s are the same length.

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The study found women with ‘masculine’ finger ratios are less likely to develop the disease than those with a ‘feminine’ ratio. This ratio is a marker of exposure to hormones in the womb and the results suggest that women who are exposed to more testosterone, or lower levels of oestrogen before birth, may be less likely to get dementia.

VEG IN DISGUISE

Sneaky ways to add veg without anyone noticing.

This week: Mashed potatoes with celeriac, carrots and swede. This recipe counts as two of your five-a-day per serving.

a bowl of food sitting on a table: Mashed potatoes with celeriac, carrots and swede © Provided by Daily Mail Mashed potatoes with celeriac, carrots and swede

Method: Peel and chop 400g potatoes and 225g each of swede, celeriac and carrot. Boil in a large pan of water until very soft, then drain.

Mash with a potato masher or use a ricer if you prefer a smoother texture. Season with salt and pepper, add a drizzle of olive oil and a tablespoon or two of Greek yoghurt. Serve straight away

TINY TWEAKS

Make nasal rinses and mouthwash part of your daily routine — a new study in the Journal of Medical Virology suggests this could help reduce transmission of viruses such as Covid. U.S. researchers tested household products such as baby shampoo (1 per cent, made up with water) as a nasal rinse, and mouthwashes, and found they could inactivate coronaviruses.

Secrets of an A-list body...

Alesha Dixon posing for a picture: Alesha Dixon wowed onlookers recently in a bright yellow mini dress © Provided by Daily Mail Alesha Dixon wowed onlookers recently in a bright yellow mini dress

HOW to get the enviable physiques of the stars.

This week: Alesha Dixon’s legs.

Alesha Dixon wowed onlookers recently in a bright yellow mini dress that showed off her toned legs.

The 42-year-old mother of two and judge on the TV show Britain’s Got Talent recently said she had completed a 12-week challenge of three workouts a week that left her feeling ‘strong’.

What to try: Try squats with heel raises.

Stand up straight, head forward, and shoulders relaxed.

Bend hips and knees to assume a squat position, keeping your feet hip-width apart.

Make sure your back is straight and head in line with your spine.

Rise up on to your toes, maintaining the squat position.

Lower heels to the floor and return to the start position.

Repeat ten times. Do two to three sets of the exercise, three to five times a week.

Read more

Drinking tea can significantly lower blood pressure .
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