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Health & Fitness On World AIDS Day: This vaginal ring could protect women from HIV in the future

20:40  01 december  2020
20:40  01 december  2020 Source:   elle.de

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A silicone ring impregnated with an antiviral drug can protect 75 percent or more of women from the AIDS virus , researchers reported Monday. And a bigger study of more than 3,000 women found those with what’s considered a healthful balance of bacteria in the vagina responded better to a drug

Teens in the study said the vaginal ring , which cuts HIV infections by 56%, was easy to use. Women and girls aged 15-24 account for a fifth of all new HIV infections globally. Experts say it frees women from relying on men to wear condoms and allows them to protect themselves confidentially.

In Germany, around 2,900 people were infected with HIV in 2019. Thus, according to the current status, 90,700 people live in this country who carry the pathogen - that of a sexually transmitted disease, which in the most common cases is transmitted from a combination of ignorance and inattention and can accompany you for a lifetime. Every year on December 1st, World AIDS Day is used to create awareness, talk about the disease and counteract stigmatization.

Welt-Aids-Tag: Vaginalring schützt vor Geschlechtskrankheit Getty Images © Getty Images World AIDS Day: Vaginal ring protects against venereal disease Getty Images

In keeping with this occasion, we would not only like to talk about the awareness of a still incurable disease, but above all to focus on the right preventive care. In addition to pre-exposure prophylaxis - better known as PrEP - a vaginal ring will in future protect women in poor countries from HIV and AIDS. Women who hardly have the opportunity to defend themselves against the sexually transmitted disease and an infection. Those who are only in the last row on the waiting list for PrEP. And are exposed to an even greater risk due to Corona.

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A vaginal implant that can block HIV could offer a cheaper, more reliable way of preventing transmission, he adds. The implant caused a significant reduction in activated T cells, indicating that it induced “an immune quiescent state” in the female rabbits’ genital tracts.

World AIDS Day is celebrated on December 1, every year to raise awareness about HIV / AIDS and to demonstrate international solidarity in the face of the pandemic. These include an increase in the spread of HIV drug resistance, which carries long-term consequences for future treatment success .

While 96 percent of HIV-infected people in Germany are supplied with drugs that stop the outbreak of the disease, this is by no means the case in every country. Around a third of the people living with HIV worldwide have no access to protective or therapeutic drugs. And it is precisely for this reason that the dapivirin ring can represent a major step in the international fight against AIDS. And also ensure the emancipation of women.

World AIDS Day: Why HIV shouldn't be forgotten, especially in Corona times.

HIV is a sexually transmitted virus that, if undiagnosed, can trigger the disease AIDS later on. In the meantime, it is no longer fatal in many countries around the world and, with the right treatment, can be contained to such an extent that HIV-infected people are no longer necessarily contagious. This is ensured by the daily intake of HIV drugs, which greatly reduce the concentration in the body and make transmission impossible. But up to now neither HIV nor AIDS is curable - which is why unprotected sexual intercourse can still lead to infection and preventive care must not be forgotten.

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World Aids Day preparations in Nepal at a rehabilitation centre and orphanage for HIV -affected women , children and victims of trafficking. We are poorly positioned. No country in the world has fully aligned its national laws and policies with the best HIV science, which is undermining the response.

Woman holding the dapivirine vaginal ring tested in the NIH-funded ASPIRE study.International It’s worth finding out why the ring worked so well in older women but not at all in the youngest women “If you could get a 61 percent efficacy in the older group, that means there is something about this

Even if AIDS is treatable in many countries, the situation is different in poor countries: The countries of South Africa are most severely affected - although here neither ideal preventive measures nor good treatment can be guaranteed. The consequences of Corona intensify this picture: The pandemic is restricting the supply of prophylactic drugs such as PrEP and a shortage of treatment options is currently leading to a worsening of the situation.

dapivirine ring: This is how it can protect women from AIDS - especially in poor countries.

PrEP is a way of protecting yourself prophylactically against the HIV pathogen - so people who have not yet become infected can ensure that when taken daily they have a high probability of not getting the virus even if they have unprotected sex with someone infected with HIV. This can, for example, facilitate the relationship with someone with HIV and give the option of having unprotected sex with one another. But especially in poor countries with a high AIDS risk like Botswana or Zimbabwe, it is difficult to get access to PrEP - especially for women. You are faced with a problem: in the worst case scenario, you cannot protect yourself from infection with the drug. In addition, it can happen that the sexual partner refuses to use a condom, that the necessary contraception is not available or the woman simply cannot bring herself to take responsibility for her health.

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This World Aids Day , we should remind governments that the fight against HIV is far from over and persuade them to continue efforts to tackle the crisis Since then, the pandemic has only added to the challenges we face in the fight against Aids . These new pressures threaten to undo the last decade

HIV , the virus that causes AIDS , is one of the world ’s most serious public health challenges. But there is a global commitment to stopping new HIV infections (New HIV infections, or “ HIV incidence,” refers to the estimated number of people who newly acquired the HIV virus during given period such as a

For this reason, there should be a vaginal ring in the future for the emancipation of women in developing countries, which, if used correctly, can reduce the likelihood of infection by more than half. The dapivirin ring is inserted into the vagina for 28 days, where it constantly transfers the prophylactic agent dapivirin against HIV pathogens to the mucous membranes. Especially in countries where the risk of AIDS is high and treatment is relatively difficult, preventive measures can make all the difference for the future. The ring is so important for women above all because they can use it discreetly - and thus have protection against HIV in their own hands. However, regularity is important for use: The dapivirin ring should be used continuously and without gaps, because this is the only way to ensure the highest level of prophylaxis. As things stand, the drug should be approved in the coming year - initially in the developing countries where it is most needed.

Better to be safe than sorry: For this reason, AIDS must continue to be an issue.

Infection with HIV and the AIDS outbreak may no longer mean a death sentence in Germany - but it remains a preventable disease that is still incurable. In this country, if diagnosed in good time, HIV can be treated well, the outbreak of AIDS can be prevented with the right medication, and life expectancy can no longer be reduced. But prevention and precaution are and will remain the key words here: Sexually transmitted pathogens such as HIV can be prevented by using a condom, regular examinations and taking prophylactic medication. At one-night stands and initial relationships, you should always insist on contraception, get tested together and continue to take the HIV infection seriously.

Because even if you can live with the disease for a long time in Germany, containment and permanent control should still be the goal. For the health of the general public. And one yourself.

The strangest medical cases of 2020 .
From a man with green urine to a teenager with a sewing pin in his heart, a number of intriguing medical cases caught our eye this year. © NEJM A man in Brazil learned he had three kidneys after receiving a CT scan for low back pain. Above, the CT scan showing the man's three kidneys: A normal-appearing kidney on the man's left side, and two kidneys fused at the pelvis. These "case reports," which describe the conditions of individual patients, don't usually have the type of broad implications that are seen in rigorous scientific studies with thousands of participants.

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