Health & Fitness Fewer than 1% of all severe COVID-19 patients are later reinfected

02:25  18 june  2021
02:25  18 june  2021 Source:   dailymail.co.uk

Professor warns people 'will be reinfected every two to four years'

  Professor warns people 'will be reinfected every two to four years' Paul Hunter, professor of medicine at the University of East Anglia, said it was normal for future strains to emerge and that they will not necessarily cause serious illness. But he warned that 'it's very difficult to predict' because 'you never really know what each new variant will do'.Government advisers are already finding that vaccines are less effective on existing variants, including as much as 30 per cent less effective on the South African one. Highly-transmissible mutations first detected in Kent and Brazil are designated 'variants of concern' and also driving a third wave across Europe.

People who have had severe COVID - 19 and worry about going through another bout of it can relax: New research finds that less than 1 % of people who've had a severe coronavirus infection get re - infected . For the study, University of Missouri researchers analyzed data from more than 9,100 Only 0.7% of patients with severe COVID - 19 infection contracted the virus a second time, with a mean re-infection period of 116 days. Of those who were re - infected , 3.2% died. Non-white patients had a higher risk of re-infection than white patients , according to the study published recently in the journal

The data suggest that repeat infections are rare — they occurred in fewer than 1 % of about 6,600 participants who had already been ill with COVID - 19 . But the researchers also found that people who become reinfected can carry high levels of the virus in their nose and throat, even when they do not And immunologist George Kassiotis at the Francis Crick Institute in London notes that participants in the study were mainly women, and mostly under the age of 60. “This group is unlikely to experience the most severe form of COVID - 19 ,” he says, “and may not be representative of the population as a whole.”

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Patients who have severe cases of COVID-19 have a very low chance of getting the virus again, a new study suggests.

Researchers from the University Missouri School of Medicine reviewed data on more than 9,000 patients who fell seriously ill and found that less than one percent tested positive again three months or more after they recovered.

The average reinfection time for those who did test positive again was three and a half months.

Non-white patients, those with asthma, and smokers were more likely to be reinfected.

The team says the findings suggest that COVID-19 reinfection is highly unlikely, but possible, but note the research was done before variants - like the Indian Delta variant, which may be more likely to reinfect - started circulating.

The enduring scars of Covid-19

  The enduring scars of Covid-19 Around 10% of coronavirus sufferers still have symptoms months after being declared cured, and healthcare workers warn about a lack of resources to meet the demand for therapy servicesClose by Sheila Lozano, 24, is doing muscle-strengthening exercises on a mat to help with the breathing difficulties and joint pain that have plagued her since her “recovery” from the virus last year. Not only is there a threat of a fourth wave on the horizon, but Covid-19 has also left a range of physical and neurological effects in its wake that is undermining the daily lives of many former patients in varying degrees.

In this cohort of patients hospitalized for severe Covid - 19 who were treated with compassionate-use remdesivir, clinical improvement was observed in 36 of 53 patients (68%). Measurement of efficacy will require ongoing randomized, placebo-controlled trials of remdesivir therapy. Methods: We provided remdesivir on a compassionate-use basis to patients hospitalized with Covid - 19 , the illness caused by infection with SARS-CoV-2. Patients were those with confirmed SARS-CoV-2 infection who had an oxygen saturation of 94% or less while they were breathing ambient air or who were receiving oxygen

Severe illness means that the person with COVID - 19 may require hospitalization, intensive care, or a ventilator to help them breathe, or they may even die. People of any age with certain underlying medical conditions are also at increased risk for severe illness from SARS-CoV-2 infection. Pregnant HCP should follow risk assessment and infection control guidelines for HCP exposed to patients with suspected or confirmed COVID - 19 . Adherence to recommended infection prevention and control practices is an important part of protecting all HCP in healthcare settings.

a man talking on a cell phone: Got COVID once? You are unlikely to test positive again, a new study shows © Provided by Daily Mail Got COVID once? You are unlikely to test positive again, a new study shows chart: Slightly more patients were reinfected within shorter time intervals, possibly reflecting long COVID infections © Provided by Daily Mail Slightly more patients were reinfected within shorter time intervals, possibly reflecting long COVID infections

After recovering from an illness, patients usually have some degree of immunity  because their immune systems remember the disease to prevent it from wreaking havoc a second time.

However, the length of time this immunity lasts - and how well it works - is different for every disease.

When it comes to COVID-19, scientists are still working to understand this natural immunity and if there is a threshold for immunity.

Researchers have documented a few cases of reinfection - patients who get sick with COVID-19 a second time, after their initial recovery. COVID reinfections are known to be rare, though not impossible.

Just 0.01% of Americans who have received vaccine were reinfected

  Just 0.01% of Americans who have received vaccine were reinfected A new CDC report published on Tuesday found that 10,262 of 101 million Americans fully vaccinated against COVID-19 - 0.01% - this year later tested positive for the virus.So-called 'breakthrough cases' occur when people test positive for coronavirus at least 14 days after receiving their final dose of the vaccine.

Early administration of high-titer convalescent plasma against SARS-CoV-2 to mildly ill infected older adults reduced the progression of Covid - 19 . Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness. Methods: We conducted a randomized, double-blind, placebo-controlled trial of convalescent plasma with high IgG titers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in older adult patients within 72 hours after the onset of mild Covid - 19 symptoms.

With fewer than 10% of residents vaccinated and hospital beds filling up as new Covid - 19 variants spread, Moscow's Mayor has warned that the Russian capital might be facing a short but very strict lockdown to control the virus. “We are very close to much more severe – temporary, but severe – decisions on restrictions,” Sergey Sobyanin said on Thursday. He noted that 600 Covid - 19 patients have been hospitalized over the past 48 hours, and that Moscow has about 17,000 beds dedicated to coronavirus patients to date. Soon that number will exceed 20,000, he added, and “no European city

In the new study, published in Clinical Infectious Diseases, researchers used an anonymized COVID-19 dataset to look at electronic records of COVID cases in 62 healthcare facilities across the U.S.

The researchers identified over 9,000 patients who recovered from severe Covid between December 2019 and November 2020.

To qualify for the analysis, patients needed to test positive, visit the hospital during their initial case, and get COVID tested at least four times during the study period.

And to be considered a COVID-19 reinfection, a patient needed to test positive over 90 days after recovering from their initial bout with the disease.

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Out of 9,119 patients in total who were studied, just 63 got the virus a second time., meaning the reinfection rate was just 0.7 percent.

COVID patients left the hospital in worse condition than they arrived

  COVID patients left the hospital in worse condition than they arrived At Michigan Medicine, 45 percent of COVID patients left the hospital in a worse health state than their arrival. Many patients weren't able to go home and live independently after their stay.Researchers at Michigan Medicine found that 45 percent of patients hospitalized for COVID saw significant health declines after they were released.

Other symptoms of COVID - 19 are improving*. *Loss of taste and smell may persist for weeks or months after recovery and need not delay the end of isolation. Most people do not require testing to decide when they can be around others; however, if your healthcare provider recommends testing, they will let you know when you can resume being around others based on your test results. Note that these recommendations do not apply to persons with severe COVID - 19 or with severely weakened immune systems (immunocompromised).

Science ’s COVID - 19 reporting is supported by the Pulitzer Center and the Heising-Simons Foundation. Continuing the spate of stunning news about COVID - 19 vaccines, the biotech company Moderna announced the final results of the 30,000-person efficacy trial for its candidate in a press release Moderna received $ 1 billion from the U.S. government’s Operation Warp Speed to help develop its mRNA vaccine. (Pfizer passed on such development money, but has signed an advanced purchase order for its vaccine with Warp Speed.) Moderna CEO Stéphane Bancel says all of the federal money

The researchers found that non-white patients were at higher risk of reinfection than white patients.

Smokers - or those with nicotine dependence - and patients with asthma were also more likely to be reinfected.

a group of people looking at a cell phone: Patients who smoked or suffered from asthma were more likely to be reinfected © Provided by Daily Mail Patients who smoked or suffered from asthma were more likely to be reinfected

Patients were less likely to experience severe COVID-19 complications - such as heart failure and pneumonia - during their second infections.

Of those 63 patients who were reinfected, only two died from the virus during their second infection.

The researchers noted that the reinfected patients may have had less severe cases in their second bout with COVID-19 because they still had antibodies left from the first round.

But this pattern may also be attributed to the fact that doctors have gotten much better at treating COVID-19 patients since the pandemic started.

The average time for reinfection was three and a half months.

When the researchers calculated reinfection rates for shorter time frames, however, the rates were slightly higher - 2.2 percent of patients tested positive again after 45 days, for example.

Neurological symptoms likely in both mild and severe COVID patients

  Neurological symptoms likely in both mild and severe COVID patients Brain- and nervous system-related COVID symptoms like loss of smell are incredibly common - in both patients with mild and severe COVID cases - a new study found.Researchers from University College London included more than 100,000 patients included in the meta-analysis, and found the most common symptoms were loss of smell, weakness, and fatigue.

In some of these cases, the COVID-19 patients may have been experiencing 'long Covid' - symptoms over an extended timeframe.

Reinfection rates also tend to be higher when researchers examine longer timeframes, such as over a year. Natural immunity from COVID-19 does not last as long as immunity from a vaccine.

chart, histogram © Provided by Daily Mail   Fewer than 1% of all severe COVID-19 patients are later reinfected © Provided by Daily Mail

While this study suggests that COVID-19 reinfection is very rare, it relies on data that only extends to November 2020 - before dangerous coronavirus variants began circulating.

We now know that some variants - such as the Delta variant from India - are more likely to reinfect patients after they recover.

The vaccines currently in use in the U.S. work well against Delta, however.

'This is one of the largest studies of its kind in the U.S., and the important message here is that COVID-19 reinfection after an initial case is possible, and the duration of immunity that an initial infection provides is not completely clear,' said lead author Dr Adnan Qureshi, a professor of clinical neurology at the MU School of Medicine.

Qureshi and his colleagues suggest that survivors from COVID-19 should not relax their compliance with other public health interventions - and that they should get vaccinated if possible.

  Fewer than 1% of all severe COVID-19 patients are later reinfected © Provided by Daily Mail Read more

Convalescent plasma works well for cancer patients with severe Covid .
Cancer patients suffering from COVID who were treated with convalescent plasma were 86% less likely to die. Only 13% of the patients who received this treatment died, versus 25% who did not.Researchers found that patients were 86 percent less likely to die if they were given blood plasma from a recovered coronavirus patient than those on standard therapy.

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