US News An American committee recommends the Pfizer vaccine for 5-11 years

05:05  27 october  2021
05:05  27 october  2021 Source:   lepoint.fr

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U N US Committee of Experts voted on Tuesday in favor of the immunization of 5-11 years with the VACCINE Against Pfizer -Biontech, a very future authorization of the cure for some 28 million children in the United States . The opinion of this committee is only advisory, but it is rare that it is not followed by the US Medicines Agency (FDA). If it actually authorizes the vaccine for this age group, the injections could begin in early November. gathered by Pfizer and the health authorities.

After a day of discussion, broadcast live on the Internet, its members felt that the profits of the vaccine for children aged 5 to 11 prevailed over the risks (17 votes for, absent). The children "are far from being spared by the damage of COVID-19," said Peter Marks, from the FDA, in the introduction. In the 5 to 11 years old, more than 1.9 million cases of COVID-19 have been recorded since the beginning of the pandemic in the United States, more than 8,300 hospitalizations, and a hundred death, has it detailed. Children caught the virus can develop a pediatric multi-systemic inflammatory syndrome (MIS-C), or a "Long Covid".

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Children "play an important role in the transmission" of the

virus to support its application for authorization, Pfizer has presented the results of a clinical trial that has demonstrated a 90.7% efficiency of the vaccine to prevent the symptomatic forms of The disease among 5 to 11 years old. "Vaccination will help ensure in-person learning" at school, "crucial for children's development," argued William Gruber, Manager at Pfizer. In addition, children "play an important role in the transmission" of the virus in the general population, he added. Prior to the meeting, the FDA had published its own data interpretation, pointing clearly in favor of authorization.

The main debate is the risk of myocarditis caused by the vaccine. This inflammation of cardiac muscle is a side effect that has been detected in adolescents and young adults (mostly male) after Pfizer or Moderna. The health authorities have confirmed nearly 880 cases (more than 600 remains to be evaluated), of which approximately 830 required hospitalization. At least about 790 have since returned home, and no deaths have been recorded.

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among the 3,000 children vaccinated in total during the clinical trials of Pfizer, no case of myocarditis has been detected. Experts believe that this side effect should be rarer in young children because it could be related to testosterone levels. This does not mean that the risk is absent. But the FDA analysis predicts that the number "clinically significant problems" related to CVIV-19 avoided through the vaccine "Clearly swing the surplus of myocarditis cases". Dr. Paul Offer, a member of the committee, was reassured by the fact that the dosage for children is lower (10 micrograms per injection instead of 30 for older groups). Many experts still felt that the question was difficult to decide, and emphasized the need to monitor the data once the immunization campaign launched.

Parents to be convinced

when the FDA has given its green light, an expert committee of the prevention and disease control centers (CDC) will meet in turn on 2 and 3 November on the subject, And this federal agency will then publish its recommendations for health professionals administering doses. As for adults and adolescents, the vaccine requires two injections, three weeks apart.

Children's bottle caps will be orange, and thus easily recognizable compared to the purple caps of the bottles for older groups. The White House indicated to be ready to send the country millions of doses to four corners. Children can be vaccinated in pediatricians, pharmacies or some schools. But still will he have to convince. According to a survey of the Kaiser Family Foundation at the end of September, about one-third of the parents declared that they would vaccinate their child as soon as possible, another third party they would wait before making a decision, and a quarter they would not do. vaccinate.

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