US News Novartis issues security information to the most expensive medication in the world: Two children die in treatment with the most expensive drug in the world

10:50  12 august  2022
10:50  12 august  2022 Source:   blick.ch

inflation in Turkey increases to almost 80 percent

 inflation in Turkey increases to almost 80 percent in Turkey, inflation continues to attract at a very high level. In July, consumer prices rose by 79.6 percent compared to the same month, as the National Statistics Office announced on Wednesday in Ankara. Analysts had expected an even higher inflation rate of an average of 80.2 percent. In the previous month, the inflation rate had 78.6 percent. In July, consumer prices rose by almost 2.4 percent in July. © Lefteris Pitarakis/AP/dpa The lira crisis continues to drive inflation in Turkey.

Two children died after treatment with Zohnensma, the most expensive drug produced by Novartis. Novartis names organ failure as the cause of death. The pharmaceutical company remains convinced of the “overall favorable risk-benefit profile of Zolgensma”.

Zwei Kinder sterben bei Behandlung mit teuerstem Medikament der Welt © provided by Blick Two children die during treatment with the most expensive drug in the world

The gene therapy Zöngensma produced by the Swiss pharmaceutical company is considered the most expensive drug in the world. A single injection into the spinal cord costs the equivalent of around two million francs. Novartis reported on Thursday that two patients died of acute liver failure after treatment with Zolgensma.

When Covid comes back after treatment with Paxlovid

 When Covid comes back after treatment with Paxlovid that a covid disease can return with the Paxlovid medication shortly after therapy, has been known for months. The US health authority CDC sees the very rare phenomenon. © Philipp of Ditfurth/dpa The drug Paxlovid for the treatment of Covid-19 reduces the viral load and thereby gives the body time to build up its own immune defense against the virus. Such a “Covid rebound” usually occurs two to eight days after an initial recovery, she wrote in May.

Novartis notified the health authorities of the markets in which the drug is approved. "Although this is an important security information, but not a new security signal," said the Basel pharmaceutical company in a statement that Reuters has. Novartis "believes in the overall favorable risk benefit profile of Zengensma". Nevertheless, "the labeling will be updated to point out that liver failure has been reported on fatal acute acute."

Liver failure several weeks after the infusion

The victims are two children in Russia and in Kazakhstan. The fatal organ failure was "after a five- to six-week umensma infusion", a few days after the start of corticosteroid treatment. According to Novartis, the first fatal cases of acute liver failure are.

Zengensma has been approved in the Russian Federation since the end of 2021. The drug for children aged less than two years is currently one of three medication worldwide that are used to treat spinal muscle atrophy. This is a rare hereditary disease that often ends fatally at the age of two.

Zengensma was approved in the United States in May 2019 and is only the second genetic therapy for an inherited disease approved by the FDA. In addition to Zollgensma, there are only two other medication from Biogen and Roche, which have so far been approved for the treatment of spinal muscle atrophy. (Kes/Lui)

"I took my friends in my arms and drunk alcohol": in Finland, the last very festive evening of the Prime Minister is debated .
© Matias Honkamaa / AFP The Finnish Prime Minister Sanna Marin explains In front of the press on August 18, 2022, after the broadcast of compromising videos. This is the " Finland Gate " of summer. In videos that have been circulating since Wednesday on social networks, the Finnish Prime Minister Sanna Marin , 36, appears unleashed with her friends.

usr: 2
This is interesting!