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Health & Fit A compound in beets could slow Alzheimer's effects

21:32  21 march  2018
21:32  21 march  2018 Source:   nydailynews.com

This May Be The 1st New Alzheimer's Drug In Years

  This May Be The 1st New Alzheimer's Drug In Years A drug originally designed to treat diabetes has reversed Alzheimer's disease symptoms in lab mice.In the study, published online this week in Brain Research, scientists from Lancaster University in England used lab mice to test how effective a diabetes drug known as a triple receptor was in treating Alzheimer’s disease. The mice in the study were specifically created to express certain genes associated with Alzheimer's disease in humans. The researchers waited for the mice to age before giving them the drug, therefore giving their disease some time to develop and damage the animal’s brain.

Betanin, the compound that gives beets their distinctive red color could slow down the effects of Alzheimer ' s disease — the world's leading type of dementia. Misfolded protein accumulation in the brain — one of the processes associated with Alzheimer ' s diseases — could be slowed with the

Betanin, the compound that gives beets their distinctive red color could slow down the effects of Alzheimer ' s disease — the world's leading type of dementia.

Betanin, the compound that gives beets their distinctive red color could slow down the effects of Alzheimer's disease — the world's leading type of dementia.

Misfolded protein accumulation in the brain — one of the processes associated with Alzheimer's diseases — could be slowed with the help of the vegetable and lead to the development of a drug aimed at alleviating some of the illness' long-term, debilitating effects, according to a new study.

A compound in beets that gives the vegetable its bright coloring could have Alzheimer’s-fighting properties. © sagarmanis/Getty Images/iStockphoto A compound in beets that gives the vegetable its bright coloring could have Alzheimer’s-fighting properties.

The compound "shows some promise as an inhibitor of certain chemical reactions in the brain that are involved in the progression of Alzheimer's disease," co-author Li-June Ming said in the study published by the American Chemical Society. "This is just a first step, but we hope that our findings will encourage other scientists to look for structures similar to betanin that could be used to synthesize drugs that could make life a bit easier for those who suffer from this disease."

These Non-Drug Methods Could Help People With Alzheimer's Disease, Study Suggests

  These Non-Drug Methods Could Help People With Alzheimer's Disease, Study Suggests Some non-drug strategies may help to improve cognitive skills in some people with the illness. While there are no drugs that can treat Alzheimer’s disease and reverse the memory and thinking problems it causes, a new study shows that some non-drug strategies may help to improve cognitive skills in some people with the illness.

Betanin, the compound that gives beets their distinctive red color could slow down the effects of Alzheimer ' s disease — the world's leading type of dementia. Misfolded protein accumulation in the brain — one of the processes associated with Alzheimer ' s diseases — could be slowed with the

Betanin, the compound that gives beets their distinctive red color could slow down the effects of Alzheimer ’ s disease — the world’s leading type of dementia. In the study, the researchers saw that introducing betanin reduced oxidation by 90% and, in effect , at least partly suppressed misfolding.

Alzheimer's affects one in 10 Americans over the age of 65 and one in three over 85 — more than five million people. The cause of the disease is still mostly unknown, but scientists suspect that a big contributor is beta-amyloid — a peptide that builds up in the brain and disrupts neuron communication, eventually killing them off. When beta-amyloids attach themselves to metals in the brain like copper or iron, they oxidize, misfold and accumulate.

In the study, the researchers saw that introducing betanin reduced oxidation by 90% and, in effect, at least partly suppressed misfolding.

"We can't say that betanin stops the misfolding completely, but we can say that it reduces oxidation," co-author Darrell Cole Cerrato said. "Less oxidation could prevent misfolding to a certain degree, perhaps even to the point that it slows the aggregation of beta-amyloid peptides, which is believed to be the ultimate cause of Alzheimer's."

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Could Insulin Hold the Answer to Cause of Alzheimer's? .
Evidence suggests that diabetes drugs might be an effective treatment for Alzheimer's patients.Johnson and Johnson recently announced that it was halting a clinical trial for a new Alzheimer’s drug after safety issues emerged. This latest failure adds to the dozens of large, costly clinical trials that have shown no effect in treating this devastating disease.

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