Certain anticholinergic drugs tied to 30% higher dementia risk, study finds
Many older adults know that long-term use of certain medications can negatively affect cognition and increase one's risk of dementia.But a new study suggests that some classes of anticholinergic drugs -- particularly those used to treat depression, Parkinson's and urinary incontinence -- carry a higher risk than others.
A new study found adults in the U.S. are using prescription drugs that can lead to depression and suicide . Approximately 15 percent of adults who were simultaneously taking three or more commonly prescribed drugs experienced depression , a study found.
of adults in the United States are using prescription medications that could potentially cause depression or increase the risk of suicide . in the Journal of the American Medical Association, the study examined the medication - use patterns of more than 26,000 adults from 2005 to 2014.
More than one-third of adults in the United States are using prescription medications that could potentially cause depression or increase the risk of suicide.
Researchers from the University of Illinois at Chicagomay be using medications with these potential risks, but because they are so common and many times don't have anything to do with depression, health care providers and patients are unaware of the dangerous side effects.
Study triples number of known depression genes
A study of nearly half-a-million people has uncovered 30 new genes linked to depression, tripling the number known to play a role in the debilitating disease. The same enlarged basket of depression genes also underpins other psychiatric disorders, such as schizophrenia, a consortium of nearly 250 scientists discovered."This is a game changer," said Patrick Sullivan, director of the Center for Psychiatric Genomics at the University of North Carolina and co-leader of the research. The findings, published in Nature Genetics, provide targets for new drugs and other forms of treatment.
The researchers retrospectively analyzed medication use patterns of more than 26,000 adults from “The take away message of this study is that polypharmacy can lead to depressive symptoms and “With depression as one of the leading causes of disability and increasing national suicide rates, we
The researchers retrospectively analyzed medication use patterns of more than 26,000 adults from "The take away message of this study is that polypharmacy can lead to depressive symptoms and "With depression as one of the leading causes of disability and increasing national suicide rates, we
Published Wednesday in the Journal of the American Medical Association, the study examined the medication-use patterns of more than 26,000 adults from 2005 to 2014. Researchers discovered that more than 200 commonly used prescription drugs, including hormonal birth control medications, blood pressure and heart medications, proton pump inhibitors, antacids and painkillers, have depression or suicide listed as potential side effects.
Researchers found that approximately 15 percent of adults who used three or more of these medications simultaneously experienced depression, compared to 5 percent not taking the drugs, 7 percent taking only one drug and 9 percent taking two drugs at the same time.
Researchers observed the symptoms in drugs that listed suicide as a side effect but also saw similar results when they excluded participants taking psychotropic medications, which is considered an indicator of underlying depression unrelated to medication use.
Depression skyrockets in teens, young adults
Major depression is on the rise among Americans from all age groups, but is rising fastest among teens and young adults, new health insurance data shows.Depression rates also vary a lot state by state, with Rhode Island having the highest rate of depression at 6.4 percent. Hawaii has the lowest rate — 2.1 percent.
While depression does appear to have biological components, it is certain that psychological and social factors also play a vital role. The loss of a loved one or a disappointment may trigger a depression ; past losses, perhaps not fully acknowledged, often make someone more vulnerable to depression .
The study noted an increased incidence of depression in individuals without health insurance coverage versus those who had coverage (5.9 Suicide is estimated to be the eighth leading cause of death in all age ranges in the United States. The highest suicide rates are found in men older than
The study was the first to show that use of these types of drugs at the same time was associated with a greater likelihood of depression. It also shows the increase in polypharmacy, the concurrent use of multiple medications, for medications with depression and suicidal symptoms as side effects.
"The takeaway message of this study is that polypharmacy can lead to depressive symptoms and that patients and health care providers need to be aware of the risk of depression that comes with all kinds of common prescription drugs – many of which are also available over the counter," Dima Qato, lead author and assistant professor of pharmacy systems, outcomes and policy in the UIC College of Pharmacy, said in a press release. "Many may be surprised to learn that their medications, despite having nothing to do with mood or anxiety or any other condition normally associated with depression, can increase their risk of experiencing depressive symptoms, and may lead to a depression diagnosis."
Understanding your treatment options for depression
Risk factors for depression can include a personal or family history or a stressful life event - like a move, or loss of a loved one. Depression is a medical illness - and not a weakness or moral failing. While it's not really known what's going on in the brain to cause depressive symptoms, it is well known that brain chemical imbalances are the cause of depression. The good news is that multiple treatments are available that work, help manage symptoms, and lower the risk of recurrence.
1 In 3 Adults In The U.S. Takes Medications Linked To Depression . And depression is a potential side effect of many of them. Glasshouse Images/Getty Images hide caption. Use of medications with depression or suicidal thoughts as potential side effects has been on the rise, according "With depression as one of the leading causes of disability and increasing national suicide rates, we need
More than 200 medications have depression as a listed side effect; nutritional deficiencies and many other Thirty-eight percent of American adults are on one or more medications that can cause With depression ,4 anxiety and suicide all on the rise, it's becoming increasingly crucial to get to the "The take away message of this study is that polypharmacy can lead to depressive symptoms and
In addition to the increase of polypharmacy, the study found an increase in the use of medications with depression and risk of suicide as adverse side effects. Qato said further investigation needs to be done on drug-drug interactions so that health care professionals can recognize if patients are using multiple medications that increase the risk of depression or suicide.
Slideshow: 13 symptoms of serious health matters (Courtesy: Mom.me)
Depression Linked to Low Levels of Brain Molecule .
The discovery could help researchers create a blood test to diagnose depression. Depression could one day be diagnosed with a blood test thanks to a study that has found a link between the mental condition and a molecule in the body. A team of researchers in the U.S. found patients with major depressive disorder (MDD) have lower levels of a molecule called acetyl-L-carnitine (LAC) in their blood.MDD, also known as clinical depression, is characterized by a persistent low mood which lasts for at least two weeks.