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Health & Fit Synthetic opioids even more deadly, CDC says

17:59  12 july  2018
17:59  12 july  2018 Source:   nbcnews.com

Fatal accidents involving drugs surpasses alcohol-related crashes: report

  Fatal accidents involving drugs surpasses alcohol-related crashes: report A report by the Governor’s Highway Safety Association stated fatal car crashes involving drugs has surpassed those related to alcohol in the past decade.A new report published Thursday found that fatal car crashes involving marijuana, opioids and drug use have increased over the past decade and surpassed incidents related to alcohol.

Deaths from these drugs nearly doubled from 2016 to 2017, the CDC said . Other illicit synthetic opioids include furanylfentanyl and acrylfentanyl. Large U.S. cities see big jump in deadly opioid overdoses, CDC data shows. “Ohio alone reported more than 1,700 opioid overdose deaths testing

The first wave began with increased prescribing of opioids in the 1990s 2, with overdose deaths involving prescription opioids (natural and semi- synthetic opioids and methadone) increasing since at least 1999. Read more about CDC ’s role in the opioid overdose epidemic.

Image: embers of the Hazmat unit respond to the scene of an overdose that killed two peopleMembers of a hazmat team at the scene of a suspected carfentanil overdose that killed two people in Lawrence, Massachusetts, on July 17, 2017. Authorities alerted the team because exposure to even a small amount of carfentanil can cause serious injury or death. © Provided by NBCU News Group, a division of NBCUniversal Media LLC Image: embers of the Hazmat unit respond to the scene of an overdose that killed two peopleMembers of a hazmat team at the scene of a suspected carfentanil overdose that killed two people in Lawrence, Massachusetts, on July 17, 2017. Authorities alerted the team because exposure to even a small amount of carfentanil can cause serious injury or death. Overdose victims may need extra naloxone, the agency warns.

New synthetic opioids are killing more people than ever before, with more than half of all opioid overdose deaths caused by the powerful, lab-made drugs, federal officials said Wednesday.

More people may die from opioids than thought

  More people may die from opioids than thought Some states don't classify opioid overdoses on death certificates As many as 70,000 people may have died from opioid overdoses since 1999, but were not added to the already overwhelming toll, researchers reported Wednesday.They found that in some states, many drug overdoses are so broadly classified that they are not being counted properly as opioid-related. In some states, it's as many as a third of all drug overdose deaths, the team at the University of Pittsburgh school of public health reported.

A new report from the Centers for Disease Control and Prevention says opioids are a factor in That’s how much the death rate due to synthetic opioids increased among Latinos and Asians and The number of "waves" in the epidemic of opioid overdose deaths, according to the CDC researchers.

“No area of the United States is exempt from this epidemic—we all know a friend, family member, or loved one devastated by opioids ,” said CDC The overdose death rate from synthetic opioids (other than methadone) more than doubled, likely driven by illicitly manufactured fentanyl (IMF).

The Centers for Disease Control and Prevention issued a Health Alert Network warning about the increased supply of the illicit drugs, which are many times stronger than fentanyl, the prescription painkiller.

"The dramatic rise in the supply of illicitly manufactured fentanyl and fentanyl analogs has been mirrored by an equally dramatic rise in deaths involving synthetic opioids other than methadone, a category which includes fentanyl and fentanyl analogs," the CDC said in its alert.

Death rates doubled between 2015 and 2016, the CDC said. "More than 55 percent of opioid overdose deaths occurring nationally in the 12 months ending November 2017 involved synthetic opioids, accounting for more than 27,000 overdose deaths," the CDC said in the health alert, citing preliminary numbers.

Tainted synthetic pot threatens blood supply, FDA warns

  Tainted synthetic pot threatens blood supply, FDA warns The FDA said it has received several reports of blood donors who have used products such as K2 and "spice" contaminated with an ingredient in rat poison. Synthetic cannabis products such as K2 and "spice" are being contaminated with a rat poison ingredient that threatens not only people who use them, but also the blood supply as a whole, the Food and Drug Administration said Thursday.Hundreds of people in 10 states have shown up in hospitals with symptoms such as severe bleeding and seizures after using such products, the FDA said.

Consider CDC ’s opioid prescribing guideline for chronic pain, which helps primary care providers offer safer, more effective care. MMWR: Trends in deaths involving heroin and synthetic opioids excluding methadone and drug product reports by U.S. Census region, United States — 2006–2015.

According to the CDC , much of the increase in fatal opioid overdoses was driven by the rise in illegal synthetic opioids other than methadone, such as fentanyl and “This means that even if you ignored deaths from all other drugs, the opioid epidemic alone is deadlier than the AIDS epidemic at its peak.”

That's up from 20,000 overdose deaths from synthetic opioids in 2016.

People who overdose on the synthetics may need multiple doses of naloxone, the drug that can reverse an overdose, the CDC added.

The new drugs include carfentanil, which is 100 times more potent than fentanyl, the CDC said. Another is 3-methylfentanyl, which is four times as powerful. Deaths from these drugs nearly doubled from 2016 to 2017, the CDC said.

Other illicit synthetic opioids include furanylfentanyl and acrylfentanyl. "Finally, drug submissions testing positive for a synthetic illicit opioid known as U-47700, first encountered by the DEA in 2016, increased from 533 submissions in 2016 to 1,087 during January-June, 2017," the CDC said in the alert, referring to the Drug Enforcement Administration.

Some of the new drugs may not be detected by standard tests, and coroners and medical examiners may need to use a mass spectrometer to detect the substances.

Kentucky drug overdose deaths jump 11.5 percent in 2017

  Kentucky drug overdose deaths jump 11.5 percent in 2017 Drug overdose deaths in Kentucky are increasing despite a drop in opioid prescriptions and heroin use. The result is nearly 100 million fewer opioid prescriptions in 2017 — and an 11.5 percent increase in drug overdose deaths.

Death rates from synthetic opioids , including fentanyl, increased 72.2% from 2014 to 2015, the US Centers for Disease Control and Prevention said Friday. There were more than 33,000 opioid deaths in 2015, the CDC says .

One of the most dangerous drugs is a synthetic opioid ‘so potent and that even a microgram “It is so potent and so deadly that even a microgram amount can kill someone,” said Drug Meanwhile in Ohio there were 1,245 fentanyl seizures in 2014, the most of any state according to the CDC .

And they're often being used to cut other drugs, such as cocaine, the CDC said.

The U.S. is suffering through a terrible epidemic of opioid abuse. Opioids, including prescription opioids and heroin, killed 42,000 people in 2016, the CDC says. Opioid overdose deaths are so bad that they have helped drive down U.S. life expectancy.

Starting in 2016, most deaths were caused by the street synthetics. That continued into 2017, the CDC said. "This 12-month sum of synthetic opioid overdose deaths exceeds the total number of all opioid overdose deaths in 2013, when deaths involving synthetic opioids first began to climb," the CDC said.

"Ohio alone reported more than 1,700 opioid overdose deaths testing positive for fentanyl analogs during July 2016-June 2017, with more than 1,100 of those deaths involving carfentanil."

Emergency responders and physicians may not know that people overdosing on the synthetics may need extra care, the CDC said.

"Orally ingested counterfeit pills laced with fentanyl or fentanyl analogs may require prolonged dosing of naloxone in the ED hospital setting due to a delayed toxicity that has been reported in some cases," the CDC said

Synthetic Cannabinoids Causing Severe Bleeding .
<p>Wisconsin is urging users of synthetic cannabinoids to immediately stop using the products after dozens of people suffered from severe bleeding caused by ingesting rat poison.</p>The Wisconsin Department of Health Services (DPHS) announced in a press release that the state is continuing to see cases of severe bleeding stemming from the use of synthetic cannabinoids, often called “fake weed,” “K2” and “spice.

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