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Health & FitStudy Links Heartburn Drugs to Fatal Illnesses

00:13  06 june  2019
00:13  06 june  2019 Source:   247tempo.com

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Extended use of popular drugs to treat heartburn , ulcers and acid reflux has been associated with an increased risk of premature death. Other researchers independently have linked PPIs to adverse health problems such as dementia, bone fractures, heart disease and pneumonia, among others.

CHICAGO, May 30 (Xinhua) -- A study has linked long-term use of drugs known as proton pump inhibitors (PPIs), usually used to treat heartburn , ulcers and acid reflux, to fatal cases of cardiovascular disease, chronic kidney disease and upper gastrointestinal cancer. The study , conducted by

Study Links Heartburn Drugs to Fatal Illnesses© Daniela Jovanovska-Hristovska / Getty Images

Proton pump inhibitors (PPIs) -- a widely prescribed group of medications that combat heartburn, GERD (gastroesophageal reflux disease), and ulcers -- are the most widely prescribed class of drugs worldwide, with annual global sales of about $13 billion. More than 15 million Americans take the drugs, both prescription-strength and the commonly available over-the-counter versions.

These drugs might ease digestive discomfort and stave off gastroesophageal problems, but they might also be extremely hazardous to your health -- even though they’re not generally considered to be among the 25 most dangerous drugs.

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New research suggests that drugs commonly used for heartburn , acid reflux, and ulcers may raise the risk of numerous fatal conditions, including heart disease and stomach cancer. A new study warns about the dangers of a class of drugs called proton pump inhibitors.

Extended use of popular drugs to treat heartburn , ulcers and acid reflux has been associated with an increased risk of premature death. Other researchers independently have linked PPIs to adverse health problems such as dementia, bone fractures, heart disease and pneumonia, among others.

A new study conducted by researchers at Washington University School of Medicine in St. Louis and the city’s Veterans Affairs Health Care System, following up on research they conducted in 2017, suggests that such commonly used drugs as Nexium, Prilosec, Prevacid, and Protonix put those who take them at risk for premature death from kidney and heart disease and stomach cancer. They have also been linked to digestive hormone imbalances and increased risks for pneumonia, dementia, and bone fractures.

Using anonymous medical records from the U.S. Department of Veterans Affairs between 2002 and 2004, the researchers studied 157,625 mostly Caucasian men age 65 and older who had been newly prescribed PPIs and another 56,842 who had been newly prescribed a different class of drug with the same function known as H2 blockers.

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Read about heartburn causes like alcohol, caffeine, medications, drinks (juice), food (fruits), smoking, pregnancy, obesity, and medical conditions. Treatment and prevention information is included in the information.

Scientists claim common heartburn drugs like esomeprazole, which is branded as Nexium, has been linked to fatal conditionsCredit: Not known, clear with Heartburn is extremely common, affecting one in four British adult, with more than 50 million prescriptions issued each year for heartburn , ulcers

They found that users of PPIs had since died of heart, kidney, or stomach disease at the rate of 387 per 1,000 subjects, while those taking H2 blockers died from the same diseases at the rate of 342 per 1,000. Deaths from cardiovascular disease were the most common, suggesting that PPIs are yet another of the many dangerous things linked to heart problems.

While the results indicate a difference in mortality of only 45 people per 1,000, the study’s principal author, Ziyad Al-Aly, an assistant professor of medicine at the university, noted that “Given the millions of people who take PPIs regularly, this translates into thousands of excess deaths every year.”

The most alarming thing, Al-Aly added, was that more than half the people taking PPIs didn’t really need them. The study also found that more than 80% of the subjects were using low doses of prescription PPIs or over-the-counter versions. He recommended that over-the-counter PPIs should carry clear warnings about their potential health risks, and that in most cases, people shouldn’t take them for more than 14 days consecutively. More studies may have to be conducted to determine the potential danger PPIs cause and if even some of them will need to be recalled. For reference, these are the 18 of the worst drug recalls in history.

Related Video: Heartburn Drugs Linked to Fatal Diseases in New Study (Provided by KSDK-TV St. Louis)

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