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Health & FitGenes, yes, but obesity pandemic mostly down to diet: study

14:07  05 july  2019
14:07  05 july  2019 Source:   msn.com

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To tease out the relative impact of environment and genes on obesity , scientists led by Maria Brandkvist at the Norwegian University of Science and "This man's 13.9 kg excess weight is caused mostly by today's unhealthy lifestyle, but also by how his genes interplay with the environment."

To tease out the relative impact of environment and genes on obesity , scientists led by Maria Brandkvist at the Norwegian University of Science and "This man's 13.9 kg excess weight is caused mostly by today's unhealthy lifestyle, but also by how his genes interplay with the environment."

Genes, yes, but obesity pandemic mostly down to diet: study© Joanna Pecha/Istock.com About four percent of adults in the mid-1970s had a BMI of 30 or higher. By 2016, that share had risen to 13 percent (11 for men and 15 for women), according to the World Health Organization.

A three-fold jump since 1975 in the percentage of adults worldwide who are obese has been driven mainly by a shift in diet and lack of exercise, but genes do play a role as well, according a large-scale study published Thursday.

For people genetically predisposed to a wider girth, these unhealthy lifestyles compounded the problem, resulting in an even higher rate of weight gain, researchers reported in The BMJ, a peer-reviewed medical journal.

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To tease out the relative impact of environment and genes on obesity , scientists led by Maria Brandkvist at the Norwegian University of Science and "This man's 13.9 kg excess weight is caused mostly by today's unhealthy lifestyle, but also by how his genes interplay with the environment."

PARIS - A three-fold jump since 1975 in the percentage of adults worldwide who are obese has been driven mainly by a shift in diet and lack of exercise, but genes do play a role as well, according a large-scale study published Thursday. For people genetically predisposed to a wider girth, these unhealthy

The standard measure for obesity, the Body-Mass Index (BMI), is calculated on the basis of weight and height.

A BMI of 25 up to 30 means that one is overweight. Thirty and above corresponds to obesity, a major risk factor for heart attacks, stroke, diabetes and some cancers.

About four percent of adults in the mid-1970s had a BMI of 30 or higher. By 2016, that share had risen to 13 percent (11 for men and 15 for women), according to the World Health Organization.

There are currently about two billion people 18 and older -- 39 percent of all adults -- with a BMI above the "overweight" threshold of 25, and 700 million of them are clinically obese.

The prevalence of excess weight has risen even more dramatically among children, from four percent in 1975 to over 18 percent in 2016.

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PARIS (AFP) - A threefold jump since 1975 in the percentage of adults worldwide who are obese has been driven mainly by a shift in diet and lack of exercise, but genes do play a role as well, according to a large-scale study published on Thursday (July 4)

The study also looked at the genetic link to cardiovascular and metabolic health factors such as smoking, obesity , education and personality to try and understand connections with dental health. Genes , yes , but obesity pandemic mostly down to diet : study .

To tease out the relative impact of environment and genes on obesity, scientists led by Maria Brandkvist at the Norwegian University of Science and Technology combed through data on nearly 120,000 people in Norway whose height and weight were regularly measured between 1963 and 2008.

Adults began tipping the scales at significantly higher weights in the 1980s and 1990s, they found.

Those born after 1970 were far more likely to have a substantially higher BMI as young adults than earlier generations.

- 'Obesogenic' environment -

Half of the people monitored were divided into five groups depending on their genetic susceptibility to obesity.

Comparing the two groups at the extremes, the researchers found, for example, that 35-year-old men with genetic variants known to favour weight gain were already heavier in the mid-1960s than men the same age without those fat-inducing genes.

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To boost your diet efforts over time, try one a week. Shift from white bread to whole-wheat bread or a wrap. Shift from meat to seafood, or replace meat in recipes with beans and vegetables twice a week. Genes , yes , but obesity pandemic mostly down to diet : study .

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Four decades later -- even as obesity rates increased across the board -- that gap nearly doubled.

Women showed the same trend, though the increase over time was somewhat smaller.

"Genetic predisposition would make a 35-year old man of average height 3.9 kilos heavier than his genetically protected peers in the 1960s," explained Brandkvist.

"In Norway today, his vulnerable genes would make him more than 6.8 kg heavier."

In addition, he will have gained an extra 7.1 kilos "simply as a result of living in our 'obesogenic' environment," she added.

"This man's 13.9 kg excess weight is caused mostly by today's unhealthy lifestyle, but also by how his genes interplay with the environment."

While the correlation between the genetic profiles and degree of obesity was strong, the study -- by its nature -- cannot determine a direct cause-and-effect relationship, the authors caution.

Only clinical trials can highlight causal relationships, but for many areas of interest such experiments are not possible with humans, for both practical and ethical reasons.

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"Our study shows that treatment to suppress HIV replication and gene editing therapy, when given sequentially, can eliminate HIV from cells and organs of infected animals," said Kamel Khalili, Ph.D., Laura H. Carnell Professor and Genes , yes , but obesity pandemic mostly down to diet : study .

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Related video: Obesity now rivals smoking as top cause of certain kinds of cancer: study (Provided by FOX News)

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Deep South states have among the worst adult obesity rates.
The Deep South states of Alabama, Louisiana and Mississippi are among nine states where at least 35% of adults are obese. © Tetra Images/Getty Images Those findings are included in a national report released Thursday by the nonpartisan Trust for America's Health, which emphasis the health problems associated with obesity. Mississippi tied with West Virginia in 2018 for highest level of adult obesity in the nation, 39.5%. Louisiana ranked fourth with 36.8% of adults obese. Alabama was in sixth place, with a 36.2% adult obesity rate. Other U.S.

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