Health & Fit: Existing anti-parasitic medication could help fight against the Ebola virus - An effective "up to 100%" vaccine against Ebola - PressFrom - US

Health & FitExisting anti-parasitic medication could help fight against the Ebola virus

18:28  09 august  2019
18:28  09 august  2019 Source:

UN health chief warns of 'very high' risk of Ebola spread

UN health chief warns of 'very high' risk of Ebola spread The current Ebola outbreak, which is the second deadliest on record and has been confirmed to have taken nearly 1,100 lives, is so far contained to two provinces of eastern Congo that are wracked by violence by armed groups. He said the outbreak was "one of the most complex health emergencies any of us have ever faced." Video: How ready are we if ebola reaches the US? (Fox News) Your browser does not support this video require(["binding"], function (binding) { binding("wcVideoPlayer", "#video_player_13ae1890-112b-4625-b69c-c21416cba45b").

The Ebola virus caused more than 10,000 deaths in the 2014-2016 West African epidemic and more than 1,800 lives (as of August 6th) in the current outbreak in the Democratic Republic of the Congo. If effective, it could thus be easily repurposed for Ebola treatment or prevention.

Viruses are structurally different from bacteria. Viruses live and replicate inside of a human cell, they cannot live outside of this environment. Viruses insert their genetic material into a human cell’s DNA in order to reproduce.

According to scientists from the Boston Children's Hospital, an FDA-approved anti-parasitic treatment could potentially help fight against the Ebola epidemic that has been ravaging the Democratic Republic of the Congo for over a year.

Existing anti-parasitic medication could help fight against the Ebola virus© Reptile8488 / The study has demonstrated that Nitazoxanide has considerably amplified immunity to Ebola, and inhibited the virus's replication.

Scientists at the Boston Children's Hospital conducted a study on human cells in order to test the efficacy of an anti-parasitic, Nitazoxanide, for the treatment of the Ebola virus.  The study, which was published in online journal iScience, demonstrated that the treatment, which is prescribed to treat gastro-intestinal infections (caused by the Giardia and Cryptosporidium bacteria), has considerably amplified the cells' immunity to Ebola and inhibited the virus' replication.

UN says about 25% of Ebola cases could be going undetected

UN says about 25% of Ebola cases could be going undetected The World Health Organization says it may be missing a quarter of all Ebola cases in eastern Congo as violent unrest complicates detection. 

Monoclonal antibody therapies (mAbs) hold promise for the treatment of Ebola virus infections. However, mAbs are costly to produce and provide Scientists have identified an innovative antibody delivery method could offer an effective way to prevent and treat Ebola infection, potentially saving

The Fight Against Ebola . Watch the VICE News documentary here. Amendola said that the benefits of digitized records and data could be enormous because data is not readily available from previous Ebola outbreaks, and therefore extremely beneficial from a clinical standpoint.

Study director Dr. Anne Goldfeld hopes that further tests and validations will ensconce Nitazoxanide in the fight against Ebola.  "Currently, there is no easily deployable therapy for Ebola virus. There are some very promising vaccines, but there is no oral, inexpensive medication available," says Goldfeld.

Prevention and treatment for Ebola

Another advantage of Nitazoxanide: its minimal side-effect profile and appropriateness for children: If it is approved for this off-label use, it could very well become an essential part of Ebola and treatment.

Symptoms of the Ebola virus are intense fever, headaches, muscle pain, violent diarrhea, kidney and/or liver failure, and hemorrhages.

Since August 1, 2018, the Ebola virus has killed over 1,800 people in the Democratic Republic of the Congo. In July 2019, the World Health Organization qualified the epileptic as a "global public health emergency."

Read More

2 Ebola patients in Congo 'cured' with drugs, say doctors.
Two Ebola patients who were treated with new drugs in the city of Goma in eastern Congo have been declared "cured" and returned to their home. 

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This is interesting!