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Health & Fit California considers declaring common pain killer carcinogen

11:55  22 january  2020
11:55  22 january  2020 Source:   ap.org

U.S. FDA says carcinogen not found in alternatives of Zantac and its generics

  U.S. FDA says carcinogen not found in alternatives of Zantac and its generics U.S. FDA said alternatives to popular heartburn drug Zantac and its generic versions, known chemically as ranitidine, have not been found to contain the probable cancer-causing impurity that ranitidine has been linked to. (http://bit.ly/2oYJ1Vz)© golibtolibov/Getty ImagesU.S. retailers Walmart Inc, CVS Health Corp Walgreens Boots Alliance Inc and Rite Aid Corp have all removed Zantac off their shelves after some drugs containing its key ingredient ranitidine were found to have traces of the impurity, N-nitrosodimethylamine (NDMA).

(AP) — A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription and

SACRAMENTO, Calif. – A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent high-profile battles over things like alcohol and coffee.

SACRAMENTO, Calif. (AP) — A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen, echoing recent high-profile battles over things like alcohol and coffee.

This Dec. 18, 2019 photo shows generic acetaminophen capsules in Santa Ana, Calif.  A fight is coming to California over whether to list acetaminophen,  one of the world's most common over-the-counter drugs as a carcinogen, echoing recent high-profile battles for things like alcohol and coffee. (AP Photo/Chris Carlson) © Provided by Associated Press This Dec. 18, 2019 photo shows generic acetaminophen capsules in Santa Ana, Calif. A fight is coming to California over whether to list acetaminophen, one of the world's most common over-the-counter drugs as a carcinogen, echoing recent high-profile battles for things like alcohol and coffee. (AP Photo/Chris Carlson)

The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription and over-the-counter medications for adults and children, found in well-known brands like Tylenol, Excedrin, Sudafed, Robitussin and Theraflu.

UPDATE 1-FDA investigating whether Zantac causes carcinogens to form in users

  UPDATE 1-FDA investigating whether Zantac causes carcinogens to form in users The FDA is "working to understand what happens to NDMA levels in the body, after ranitidine has been exposed to acid in the stomach," according to a spokesperson.

A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent high-profile battles over things like alcohol and coffee. The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers.

A fight is coming to California over whether to list acetaminophen, one of the world's most common over-the-counter drugs as a carcinogen , echoing recent Some listings in California require warning labels. But the state has made exceptions. Alcohol has been listed as a carcinogen since 1988.

Acetaminophen has been available in the U.S. without a prescription since 1955. Concerns about its potential link to cancer come from its relationship to another drug: phenacetin. That drug, once a common treatment for headaches and other ailments, was banned by the FDA in 1983 because it caused cancer.

State regulators have reviewed 133 studies about acetaminophen, all of which were published in peer-reviewed journals. Some studies reported an increased risk of some types of cancers, while others did not. Overall, the review noted acetaminophen has been difficult to examine because it is hard to isolate it from other variables that could contribute to cancer, such as smoking.

A state law known as Proposition 65 says California must warn people of any chemical known to cause cancer or reproductive toxicity. The state's list has grown to about 900 chemicals, including toxic pesticides and flame retardants, and is more extensive than any in the U.S. Some critics say California regulators have been overzealous, requiring warning labels for countless products that confuse instead of inform consumers when the risk of cancer is disputed.

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A fight is coming to California over whether to list one of the world’s most common over-the-counter drugs as a carcinogen , echoing recent high-profile The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription

— A fight is coming to California over whether to list one of the world’s most common over-the-counter drugs as a carcinogen , echoing recent high-profile The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription

Supporters of Prop 65 say it protects not only Californians but consumers nationwide by compelling manufacturers to make products safer.

Evidence for acetaminophen's link to cancer has been weak enough that the International Agency for Research on Cancer declined to list it as a possible carcinogen following reviews in 1990 and 1999. The U.S. Food and Drug Administration has warned state officials that labeling acetaminophen as cancer-causing would be “false and misleading” and also illegal under federal law.

A panel of scientists appointed by the governor can add chemicals to this list. In 2011, the panel voted to make acetaminophen a “high priority” for consideration because it believed there was relevant evidence to consider, according to Sam Delson, spokesman for the California Office of Environmental Health Hazard Assessment.

The review process has been slow, but the panel is scheduled to have a public hearing on the listing this spring after the public comment period closes on Jan. 27.

FDA testing indicates Zantac does not form carcinogen in users

  FDA testing indicates Zantac does not form carcinogen in users The regulator said it still plans to test the drugs in human patients to fully understand whether it causes levels of the probable carcinogen N-nitrosodimethylamine (NDMA) to form in patients. Zantac, sold over-the-counter in the United States by French drugmaker Sanofi SA, and some of its generic versions, have been recalled due to possible NDMA contamination of pills that had not yet been consumed. The FDA said earlier this month it found unacceptable levels of NDMA in drugs containing ranitidine.

A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent high-profile The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription

A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent high-profile battles over things like alcohol and coffee. The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers.

“It's a difficult issue because it's a very commonly used drug. But that doesn't make any difference. That's not what our mandate is,” said Thomas Mack, chairman of the Carcinogen Identification Committee and a professor of preventive medicine at the University of Southern California.

Adding a chemical to the list can have broad repercussions. After the state listed glyphosate — widely known as the weed killer Roundup — as a carcinogen in 2017, a jury ordered the company that makes Roundup to pay a California couple with cancer more than $2 billion. A judge later reduced that award to $87 million. That's just one of the estimated 13,000 pending lawsuits involving the chemical.

That's one reason why the industry is pushing back on a potential listing. The Consumer Healthcare Products Association, a trade group representing over-the-counter medicines and dietary supplements, conducted its own review and found most studies suggest no risk for most forms of cancer, although some studies did show increased risk for kidney, liver and some forms of blood cancer.

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(AP) — A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen , echoing recent The drug is acetaminophen, known outside the U.S. as paracetamol and used to treat pain and fevers. It is the basis for more than 600 prescription and

21, 2020, at 10:54 a.m. More. California Considers Declaring Common Pain Killer Carcinogen . A fight is coming to California over whether to list acetaminophen, one of the world's most common over-the-counter drugs as a carcinogen , echoing recent high-profile battles for things like alcohol and coffee.

The association urged California regulators to have a “cautious interpretation” of studies that show an increased risk of cancer.

Some listings in California require warning labels. But the state has made exceptions. Alcohol has been listed as a carcinogen since 1988. But instead of warning labels, the state directs the alcohol industry to provide signs to California retailers to post where alcohol is sold.

Acrylamide, a byproduct of roasting coffee beans, has been listed as a carcinogen since 1990. But when a court ruling would have resulted in warning labels for coffee, state regulators stepped in and exempted the drink.

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This story has corrected the spelling of acrylamide.

Related video: Walgreens, CVS Pull Zantac Off Shelves Over Carcinogen Concerns (Provided by Newsy)

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