Health & Fit Experts explain why 2nd COVID-19 vaccine dose may have more side effects
The CDC Just Announced Who Should Get the COVID Vaccine First
Those in long-term care facilities and health care personnel should get the vaccine first, says the CDC. Read on to see what that means for you, and to ensure your health and the health of others, don't miss these Sure Signs You've Already Had Coronavirus. © Provided by Eat This, Not That! Female doctor holding COVID-19 vaccine vial and taking liquid solution out with syringe; prevention and immunization from corona virus infection.
As the coronavirus vaccinesacross the country, there have been anecdotal reports of people experiencing after the second dose, but experts say this is a "normal immune response."
Andrew Heinrich, a professor at the Yale School Of Public Health in New Haven, Connecticut, said that so far the reports of more severe side effects are "anecdotal," so there is nothing "statistically valid about that trend." However, as more people receive the shot, he said it's something that people are "aware of and starting to ask questions about."
TODAY's Al Roker evenabout dealing with related side effects before he got his second dose of the Pfizer vaccine, noting in early February that he had been hearing stories from friends that had felt more symptoms after getting the second shot.
FDA advisory committee to consider second COVID-19 vaccine, this one from Moderna, during all-day meeting
An FDA advisory panel is expected Thursday to recommend authorization of the COVID-19 vaccine developed by Moderna. It could be in states by Monday.This time, the committee is reviewing a vaccine made by Cambridge, Massachusetts, biotech Moderna, with similar technology and results as the one it supported last week by Pfizer and its German collaborator, BioNTech.
NBC News medical contributor Dr. Kavita Patel told Al that there's no reason to worry: While about a third of the people who receive the vaccine have symptoms that "seem like the flu," that's an expected immune response.
"The second vaccine (dose) — think of it as having that hit to your immune system, and your immune system now recognizes the vaccine, so it does its job," explained Patel, who said that she herself had had a reaction to the second dose. "... I felt, for about 36 hours, like I had the flu."
Dr. Bill Moss, a pediatrician and professor of infectious disease epidemiology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, agreed with Patel's assessment.
"The second dose is really like a booster dose," he said. "The immune system is seeing the vaccine for the first time with the first dose and is reacting to that, and the cells of the immune system are recruited to kind of recognize that spike protein (the part of the coronavirus that the vaccine affects). So when the body's immune system sees (the vaccine) a second time, there are more cells and there's a more intense immune response, resulting in those side effects."
Here’s where all the COVID-19 vaccine candidates currently stand
More than a dozen frontrunners have reached late-stage clinical trials.Many of the other candidates, however, will fail somewhere along the vaccine development pipeline, which includes three rounds of clinical trials with increasingly large pools of volunteers to assess their safety, efficacy, and ability to prompt a response from the immune system. And for those that achieve authorization, there remain important questions that we’ll need more time and further research to answer, including how long the immunity they offer from COVID-19 lasts.
Heinrich called the reaction a "normal immune response."
What side effects can people expect?
Side effects include localized reactions, like swelling, rash or soreness at the injection site, which have been reported in about 84% of recipients, according to Patel. About 63% of people have reported feeling some fatigue. The Centers for Disease Control and Prevention (CDC) note some people may also experience chills, fever or a headache, and suggest that people who are not feeling better after around 24 hours.
"Just be prepared," said Patel. "If you don't have a reaction, you don't need to worry that it didn't work. Every human and body is different."
Sure Signs You've Already Had COVID, According to CDC .
Sure Signs You've Already Had COVID, According to CDC