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Health & Fit Origin of multiple sclerosis: an "step important" which is hoping for treatment

20:25  15 january  2022
20:25  15 january  2022 Source:   liberation.fr

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Une représentation du virus d'Epstein-Barr. © Roger Harris A representation of the Epstein-Barr virus.

A study shows that the Epstein-Barr virus, of which 95% of adults would be infected, would be the person responsible for multiple sclerosis.

may be decisive in understanding multiple sclerosis, which affects 2.8 million people around the world. According to a new study of American researchers, this autoimmune disease could be responsible for the Epstein-Barr virus. This discovery raises hope for possible development of a future treatment.

About 95% of all adults are infected with the Epstein-Barr virus (EBV), which can also cause other diseases, such as mononucleosis. The study, published this week in the prestigious review science, shows that this virus is necessary for the development of multiple sclerosis, even if all people infected with the virus do not develop this disease.

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the hypothesis was studied For several years, but difficult to prove especially because this virus is very common, and that the symptoms of the disease begin only about ten years after the infection. This is "the first study providing convincing evidence of causality, according to Alberto Ascherio, principal author and epidemiology professor at Harvard Public Health School. It is an important step because it suggests that most cases of multiple sclerosis could be prevented by stopping the infection with Epstein-Barr virus. Aim for this virus could lead to the discovery of a cure ".

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Genetic Factors could play an

role Researchers followed more than 10 million young adults engaged in the US military, 955 of whom were diagnosed with multiple sclerosis during their service. According to this work, the risk of contracting plate sclerosis was multiplied by 32 after being infected with the Epstein-Barr virus, but remained unchanged after infection with other viruses. According to researchers from Stanford University, having published a comment of the study in the science journal, other factors, for example genetics, could play a role in developing or not developing the disease.

Multiple sclerosis is an autoimmune disease of the central nervous system (brain and spinal cord). It causes a disruption of the immune system, which attacks myelin, the sheath used to protect the nerve fibers. Evolving by "pushed", the disease is very variable from one patient to another but can lead to sequelae, and is one of the frequent causes of disability in young adults. The American laboratory Moderia announced last week having started clinical trials on humans of an Epstein-Barr virus vaccine.

Researchers identify the virus at the plate sclerosis .
This discovery raises the hope of possible development of a future treatment, which would cure this disease affecting about 2.8 million people around the world. © Provided by FranceInfo The multiple sclerosis is most likely caused by the Epstein-Barr virus, according to a new study of American researchers. For the first time, they identified a manager of this autoimmune disease. They present their results in an study published this week in the prestigious review Science (in English) .

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This is interesting!