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Entertainment Hair: How Stress Prevents Push

20:05  06 april  2021
20:05  06 april  2021 Source:   medisite.fr

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Cheveux : comment le stress les empêche de bien pousser © Adobe Stock Hair: How Stress Prevents Push

a new study reveals how stress hormones affect hair growth. Hope for the realization of a treatment against hair loss caused by chronic stress.

Stress affects the grows of your hair, it is now scientifically proven. A study of researchers from Harvard University published on March 4th in the journal Nature demonstrates how stress hormones suppress hair growth via stem cell regulation of hair follicles. Indeed the hair foluses, cavities of the skin in which the hair grows, alternate the pump and rest phases. The team led by the Ya-Chieh HSU researcher demonstrates on the mouse how corticosterone (a hormone released in times of stress, equivalent to cortisol in humans) regulates the activity of hair follicles.

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The hair foluses remain in the rest

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"Although stress has been associated with anecdotal way to many Tissue variations, including certain capillary problems, it was not clear whether it was really at the origin of these harmful changes and, more importantly, the mechanisms underlying these alterations remain poorly understood, "says HSU to The SINCILE SINCE PRESS AGENCY, relayed by the Argentin Clarin website. The researcher explains to have discovered "last year that stress depletes melanocyte stem cells (stem cells that give our hair distinctive color) by changes in the nervous system, which is at the base of grayness hair induced by stress ".

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This time, the researchers have " identified a completely different mechanism by which stress affects stem cells of the hair follicle, important to regulate the regeneration of these follicles and the growth of the hair". In practice, when the corticosterone levels are high in mice, hair follicles remain in a prolonged rest phase and do not regenerate. "In case of chronic stress, increased levels of corticosterone maintain hair follicles in a prolonged rest phase," says the study. In reversed, in the absence of corticosterone, stem cells of the hair follies are activated and the growth of new hair is activated.

A hope of treatment against hair loss

according to the authors of the study, corticosterone inhibits the activation of stem cells of the hair follicle by eliminating the production of a protein called GAS6 , of which it has been demonstrated. It promotes the proliferation of these stem cells in the absence of corticosterone. Thus, the restoration of the expression of Gas6 could overcome the inhibition induced by stress and promote the regeneration of hair growth. "These results provide the basis for exploring the treatment of hair loss caused by chronic stress ," says Rui Yi, researcher at the Northwestern University (United States).

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