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Politics Johnson & Johnson says testing shows its booster shot generates spike in antibodies

08:30  05 september  2021
08:30  05 september  2021 Source:   thehill.com

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Johnson & Johnson reported on Wednesday that receiving one of its booster shots creates a significant increase of coronavirus antibodies, one of the main defenses against infection.

a person standing in front of a fence: Johnson & Johnson says testing shows its booster shot generates spike in antibodies © Getty Images Johnson & Johnson says testing shows its booster shot generates spike in antibodies

J&J said that it conducted two studies showing that a booster shot of its vaccine created a higher increase of antibodies the second time around than after a 28-day period following the first dose being administered.

"New interim data from these studies demonstrate that a booster dose of the Johnson & Johnson COVID-19 vaccine generated a rapid and robust increase in spike-binding antibodies, nine-fold higher than 28 days after the primary single-dose vaccination," the company said in a press release as it seeks authorization for fully vaccinated individuals to get a second shot of their vaccine.

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"Significant increases in binding antibody responses were observed in participants between ages 18 and 55, and in those 65 years and older who received a lower booster dose," the company continued.


Video: Johnson & Johnson says Covid booster shot produces strong immune response (NBC News)

Currently, the Food and Drug Administration (FDA) has authorized only the Pfizer and Moderna vaccines for a booster shot in individuals who are immunocompromised.

The Biden administration has also recommended that most Americans get a third shot of either of the two mRNA vaccines, though a larger recommendation would require another independent evaluation by the FDA and the Centers for Disease Control and Prevention's (CDC) Advisory Committee on Immunization Practices.

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J&J said in their press release that they were already speaking with the FDA, CDC, European Medicines Agency (EMA) and others regarding a possible booster.

"We have established that a single shot of our COVID-19 vaccine generates strong and robust immune responses that are durable and persistent through eight months. With these new data, we also see that a booster dose of the Johnson & Johnson COVID-19 vaccine further increases antibody responses among study participants who had previously received our vaccine," Mathai Mammen, global head of Janssen research & development for Johnson & Johnson, said in a statement. "We look forward to discussing with public health officials a potential strategy for our Johnson & Johnson COVID-19 vaccine, boosting eight months or longer after the primary single-dose vaccination."

According to the CDC, more than 14 million people have received the one-shot Johnson & Johnson vaccine, far fewer than the number that has received the Moderna and Pfizer two-shot vaccinations.

Evidence for vaccine booster shots isn't clear, as Biden moves ahead anyway .
After public school enrollment declined across the country last year, school districts like the one in Lansing, Michigan, are under pressure to get students enrolled and keep them engaged as budget questions loom. Photo: Bart Thomas

usr: 1
This is interesting!