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Sport Oklahoma vs. Iowa State odds, line: 2021 college football picks, Week 12 predictions from model on 36-23 run

15:55  19 november  2021
15:55  19 november  2021 Source:   cbssports.com

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After losing to Iowa State in their third game of 2020 to fall to 1-2, the Oklahoma Sooners ran the table, winning their final eight contests -- including the Big 12 Conference title game against the Cyclones and the Cotton Bowl versus Florida. Oklahoma began the 2021 season with nine consecutive victories to run its winning streak to 17 games before suffering a 27-14 setback at Baylor last week. The 13th-ranked Sooners (9-1, 6-1) attempt to bounce back when they host Iowa State (6-4, 4-3) in a Big 12 showdown on Saturday. The Cyclones also are coming off a loss as they were edged 41-38 at Texas Tech on a field goal as time expired.

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Oct 13, 2018; Baton Rouge, LA, USA; General view of the LSU band before the game against Georgia Bulldogs at Tiger Stadium. © Provided by CBS Sports

Oct 13, 2018; Baton Rouge, LA, USA; General view of the LSU band before the game against Georgia Bulldogs at Tiger Stadium.

Kickoff at Memorial Stadium in Norman, Okla. is set for noon ET. The Sooners are 3.5-point favorites in the latest Oklahoma vs. Iowa State odds from Caesars Sportsbook, while the over-under for total points scored is 59.5. Before making any Iowa State vs. Oklahoma picks and college football predictions, you need to see what the SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

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Now, the model has set its sights on Oklahoma vs. Iowa State and just locked in its CFB picks and predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines for Iowa State vs. Oklahoma:

  • Oklahoma vs. Iowa State spread: Sooners -3.5
  • Oklahoma vs. Iowa State over-under: 59.5 points
  • Oklahoma vs. Iowa State money line: Sooners -180, Cyclones +155
  • OKLA: The Sooners are 5-0 against the spread in their last five home games against teams with winning records
  • ISU: The Cyclones are 5-1 ATS in their last six meetings with the Sooners
Featured Game| Oklahoma Sooners vs. Iowa State Cyclones
Moneyline
Spread
Total
OKLA
-180
BET NOW
-3.5
-110
BET NOW
o59.5
-110
BET NOW
IOWAST
+155
BET NOW
+3.5
-110
BET NOW
u59.5
-110
BET NOW

Why Oklahoma can cover

The Sooners are riding a nine-game home winning streak and are 28-2 in Norman under coach Lincoln Riley. They've outscored their opponents 259-116 while winning all six home games this season and have put up 52 points in each of the last two. Oklahoma won both of those contests by more than 20 points and leads the Big 12 with a 23.8-point margin of victory at home.

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Caleb Williams will start on Saturday after a hand injury temporarily kept him sidelined last week. The freshman quarterback, who replaced Spencer Rattler as Oklahoma's starter earlier this season, has thrown for 1,331 yards with 14 touchdowns and only three interceptions while also running for five scores. Ten different players have made at least one TD catch for the Sooners this year, with sophomore wideout Jadon Haselwood leading the way with six.

Why Iowa State can cover

The Cyclones have averaged 36.5 points over their last eight games, scoring 30 or more six times in that span. They also have racked up 459.1 yards of total offense during that stretch and eclipsed 400 in all but one contest. Senior Brock Purdy recorded season highs of 32 completions and 356 yards last week, giving him 2,441 passing yards on the year -- second-most in the conference.

Purdy was 32-of-42 (76.2 percent) against the Red Raiders, marking the nation-leading sixth time this season he has completed more than 75 percent of his pass attempts. Meanwhile, Breece Hall rushed for a pair of touchdowns in the loss to extend his streak to 22 consecutive games with at least one score on the ground. The junior has had a TD run in 24 of his last 25 games dating back to 2019 and is tied for fourth in the country with 16 this campaign.

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How to make Oklahoma vs. Iowa State picks

SportsLine's model is leaning over on the total, projecting 63 combined points. It also has generated an against-the-spread pick that cashes in over 50 percent of simulations. You can only get the model's Iowa State vs. Oklahoma pick at SportsLine.

So who wins Iowa State vs. Oklahoma? And which side of the spread hits over 50 percent of the time? Visit SportsLine now to see which side of the Oklahoma vs. Iowa State spread to back, all from the advanced model that is up almost $3,500 on its top-rated college football spread picks, and find out.

College football odds, lines, predictions for Championship Week, 2021: Model picks Oklahoma State, Cincinnati .
SportsLine's advanced computer model has revealed its top college football picks and bets for Championship WeekDerek Mason Vanderbilt

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