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World Pfizer Delay Compounds Canada’s Problems in Vaccine Campaign

23:39  21 january  2021
23:39  21 january  2021 Source:   msn.com

How Pfizer/BioNTech, Moderna, AstraZeneca and other leading coronavirus vaccines work

  How Pfizer/BioNTech, Moderna, AstraZeneca and other leading coronavirus vaccines work How do coronavirus vaccines work? Here's a rundown of some of the approaches.If they're positive, the company plans to apply for emergency use authorization from the US Food and Drug Administration and make the vaccine available to the public.

“The problem lies mainly with Pfizer ’s short notice announcement,” German Health Minister Jens Spahn said. Dany Fortin, who is leading Canada ’ s logistical rollout and distribution of vaccines , said Pfizer deferred next week’s deliveries entirely and that there will be a significant decline in vaccine

Pfizer compounded the problem last Friday when it announced a temporary reduction in deliveries so it could upscale its Puurs, Belgium plant, which Maj. Gen. Dany Fortin, who is leading Canada ’ s logistical rollout and distribution of vaccines , said Pfizer deferred next week’s deliveries entirely and

(Bloomberg) -- Canada came out No. 1 in the global race to secure vaccines against Covid-19, pre-ordering enough shots to inoculate its 38 million people three times over. You wouldn’t know it, though, from the pace of vaccinations.

Canada has administered about 684,000 doses, enough to give first shots to about 1.8% of the population, according to the Bloomberg Vaccine Tracker, though some people have already received two. That compares with about 7.6% in the U.K. and 5.2% in the U.S. Israel, leading all nations, has administered enough vaccine to give first shots to nearly a third of its population.

Health officials in Ottawa tried to reassure the public Thursday that the situation will improve in the spring. They released projections that 13 million people could be vaccinated by the end of June and 36 million by the end of September -- even if no additional shots are approved.

How Pfizer/BioNTech, Moderna, AstraZeneca and other leading coronavirus vaccines work

  How Pfizer/BioNTech, Moderna, AstraZeneca and other leading coronavirus vaccines work How Pfizer/BioNTech, Moderna, AstraZeneca and other leading coronavirus vaccines workIf they're positive, the company plans to apply for emergency use authorization from the US Food and Drug Administration and make the vaccine available to the public.

Pfizer told Canadian officials there would be delays in deliveries of its vaccine , but the delays now mean Canada will receive zero Pfizer -BioNTech vaccines next week. It’ s left provinces scrambling to manage the doses they have left.

Frustration visibly boiled over with some Canadian leaders Tuesday as Pfizer told the country that it would not receive any vaccine doses next week due to the continuing manufacturing disruptions at its facility in Belgium.

a close up of a door: Canada's Vaccine Rollout Hits Snags Despite Huge Orders © Bloomberg Canada's Vaccine Rollout Hits Snags Despite Huge Orders

A closed immunization clinic at the Metro Toronto Convention Centre.

Photographer: Cole Burston/Bloomberg

Canada’s campaign hit another roadblock last week, when Pfizer Inc. said it would temporarily reduce deliveries outside the U.S. as it renovates a factory in Belgium to boost capacity. Canada won’t receive any shipment from the pharmaceutical giant next week.

“Pfizer’s global supply issues are not ideal, but that’s why we were so ambitious in the large number of contracts we signed and doses we secured,” Prime Minister Justin Trudeau told reporters this week. Canada has ordered 40 million doses from Pfizer, amounting to less than 20% of the country’s commitments.

Companies scramble to expand coronavirus vaccine supply

  Companies scramble to expand coronavirus vaccine supply Pfizer and Moderna have been working to increase production and reporting success, but supply will fall short of global demand. Other vaccine companies are lagging on manufacturing. That means the United States should have 200 million doses each from the companies with authorized shots, Pfizer-BioNTech and Moderna — enough to guarantee that more than 70 percent of adults will be able to get the two-shot vaccination by the end of July. That is comparable to the share of adults some polls suggest will be willing to roll up their sleeves.

Dany Fortin, who is in charge of Canada ' s vaccine rollout, said the numbers of vaccine deliveries will start to pick back up in the first weeks of February. The pharmaceutical company told the Canadian government that Canada will not receive any of its vaccine doses next week due to delivery delays

The news comes as the Pfizer -BioNTech coronavirus vaccine reduction plan goes into effect, resulting in a vaccine delivery hold-up for Canada . THE CANADIAN PRESS IMAGES/Lars Hagberg. Canadian health officials reported 4,676 new cases of the novel coronavirus across the country on

More Than 54.3 Million Shots Given: Bloomberg Covid-19 Vaccine Tracker

The delay is a blow to Canada, where a resurgence of the virus since October has pushed hospitals closer to capacity, prompting provinces to impose new restrictions, including a curfew in Quebec. While Canada is hardly alone in its struggle to roll out the vaccine, the subdued start and the Pfizer hurdle have increased tensions between Trudeau and the provinces, and emboldened his critics.

“Canada is a proud, strong G7 nation,” Erin O’Toole, leader of the opposition Conservative Party, said in written statement Tuesday. “We cannot accept this kind of failure -- not with so much at stake.”

Canada’s vaccination ratio ranks 14th worldwide on the Vaccine Tracker, behind Ireland and Iceland and ahead of Austria, Romania and Germany. The U.S. is fifth; the contrast between the North American neighbors was highlighted in news reports showing Canadian snowbirds happily getting shots in Florida.

Asia Was a Model for How to Deal With COVID-19. Why Is It Lagging in Vaccine Rollouts?

  Asia Was a Model for How to Deal With COVID-19. Why Is It Lagging in Vaccine Rollouts? But most nations in the Asia-Pacific region, including South Korea, won't begin vaccinating citizens until February or March. New Zealand, another COVID-19 success story, won’t start vaccinating its healthcare workers until April. In the wealthy business hub of Singapore, just 6,000 people have received doses of the Pfizer-BioNTech vaccine since Dec. 30, out of a population of 5.7 million.Read More: A Year After COVID-19 Emerged, Asia Struggles to Contain Growing OutbreaksIt’s the deft handling of COVID-19 by many countries that has contributed to them becoming laggards in the vaccine race, experts say.

The doctors concur that Pfizer ’ s vaccine studies should be halted until a credible study design can be presented, one that doesn’t falsify data endpoints and The use of polyethylene glycol will also cause autoimmune reactions, a problem already being observed in U.K. patients. A 2016 study in Analytical

Canada approved the same coronavirus inoculation codeveloped by Pfizer that Britain authorized last week, and that American regulators will consider on Thursday. Background rate: How often a health problem , known as an adverse event, arises in the general population. To determine if a vaccine or a

Wrong Address

Even though Canada has secured more vaccines per capita than any other nation, “it doesn’t mean much” when the bulk is not yet being delivered, said Jean-Paul Soucy, an epidemiologist at the University of Toronto. So far only products produced by Pfizer and Moderna Inc. are authorized for use in Canada, which doubled its Pfizer order from 20 million doses last week.

Federal and provincial officials have attributed the slow pace, in part, to Canada’s expansive geography and the industrial freezer storage required for Pfizer’s vaccine, which made it difficult to cover remote areas in the world’s second-largest country by land mass.

The country’s decentralized health care system, which leaves it to each province to organize its own vaccination campaign with shots procured by the federal government, has made the rollout uneven.

Manitoba, for example, confused some people by sending the wrong address for a vaccination center, CTV News reported. Some provinces set aside shots for second doses to complete individuals’ inoculations, while others used up all their stock to give first shots to as many people as possible.

Why Israel’s Vaccine Success Might Be Hard to Replicate

  Why Israel’s Vaccine Success Might Be Hard to Replicate A credible health-care system may be the key determinant to success.It’s the kind of standout success one would expect from the now-familiar stars of the global response to COVID-19—Taiwan, South Korea, or New Zealand. But it’s actually been achieved by Israel, in several respects a surprising country to be the world’s front-runner on vaccine distribution. A 2019 Johns Hopkins study ranked Israel an unspectacular 54th among 195 countries in terms of preparedness for a pandemic. After initially appearing to vanquish the coronavirus, Israel has since suffered some of the world’s worst outbreaks—something that remains true as it celebrates its vaccine advances.

Ontario, the largest province with 14.7 million people, closed vaccination clinics over the December holidays because of low staffing. It was also slow to get vaccines into long-term care facilities, where thousands of elderly people died in the spring, Soucy said.

“Certainly, we’re behind peer nations in a lot of what we’re doing,” he said.

Canadian authorities said Pfizer will ramp up shipping and meet a target of 4 million doses by the end of March. But the disruption of deliveries forced provinces to change plans, lower their targets and cancel some appointments.

”It’s troubling, it’s a massive concern,” Ontario Premier Doug Ford said at a news conference this week, referring to the Pfizer delay. “My message to the federal government is that nothing else matters right now. Every day we’re giving out less vaccine than we have the capacity to administer is a day we lose.”

(Updates with new projections in third paragraph)

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Single-shot Johnson & Johnson vaccine 66 percent effective against moderate and severe illness .
A coronavirus vaccine that is easier to store and requires a single shot will soon be considered by regulators and could help bolster the nation’s limited supplies. The results, reported in a news release, put a third vaccine on the horizon in the United States — one with logistical advantages that could simplify distribution and expand access to shots in the United States and worldwide.

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