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World South African variant: it could immunize against other variants of the coronavirus

15:29  04 march  2021
15:29  04 march  2021 Source:   parismatch.com

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Variant sud-africain : il pourrait immuniser contre les autres variants du coronavirus © iStock South African variant: it could immunize against other variants of the coronavirus The British, South African and Brazilian variants of the coronavirus continue to circulate. If they worry, it is mainly because they are more contagious. According to a new study, the South African variant nevertheless produces a high level of antibodies capable of neutralizing other strains of Sars-CoV-2.

"501Y.V2". This is the code name used to refer to the South African variant of the coronavirus, first reported on December 18 to the South African Department of Health. Since then, it has been circulating in various countries, particularly in France. According to the epidemiological point of Public Health France dated February 25, the analysis of the results of the screening tests showed an increase in the proportion of suspected variants in France: it reached 49% for the British variant and 6% for South African and Brazilian transfers.

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Your browser does not support this video The particularities of this South African variant? "It is characterized by the presence of mutations in the regions encoding the Spike protein which give it greater contagiousness" reads a press release from

Inserm .

Although more easily transmitted, the 501Y.V2 variant would nevertheless confer some

immunity against other Sars-CoV-2 variants. In any case, this is what a new study carried out in South Africa and published on the scientific pre-publication site medRxiv reveals. The South African variant is said to produce a high level of antibodies

To find out, the scientists took plasma from people infected with the South African variant. They discovered that this one would have a "good neutralizing activity", against the classic strain of the coronavirus and potentially against the other variants.

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This research, the results of which have not yet been submitted to the scientific community for validation, indicates that out of 55 patients who were affected by the South African variant, only 4% failed to neutralize the infection. to the classic strain of Sars-CoV-2. The

antibodies conferred by the South African variant were 100% effective on the Brazilian variant, but their effects were only analyzed in seven patients.

"501Y.V2 can produce a high level of antibody capable of neutralizing it," said Tulio de Oliveira, virologist at the head of the South African Krisp laboratory. He added that the

immune response conferred by this variant was more efficient than that observed with the other variants. Covid-19: towards a vaccine based on the South African variant?

South African Health Minister Zweli Mkhize said the findings were "good news for all". And for good reason: they represent hope, because they pave the way for the creation of a vaccine based on the South African variant.

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"These results basically tell us that we have a good chance of success if we make a vaccine based on this technology," concluded Salim Abdool Karim, epidemiologist and adviser to the South African government.

Source: medRxiv, Escape of SARS-CoV-2 501Y.V2 variants from neutralization by convalescent plasma

To read also:

Vaccine against Covid-19: a third dose to fight against variants?

Covid-19: are we sick longer when we are affected by a variant?

Covid-19: what are the symptoms of the South African variant?

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