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World Top China official says efficacy of vaccines is low

06:55  12 april  2021
06:55  12 april  2021 Source:   bbc.com

Chinese Covid-19 vaccine efficacy is 'not high,' top health official admits

  Chinese Covid-19 vaccine efficacy is 'not high,' top health official admits The efficacy of Chinese Covid-19 vaccines is "not high" and authorities are weighing options to bolster protection -- including mixing different shots, China's top disease control official has said. © AP Gao Fu, director of the Chinese Center for Disease Control and Prevention, speaks at the National Vaccines and Health conference in Chengdu, Sichuan province Saturday. "The protection rates of existing vaccines are not high," Gao Fu, director of the Chinese Center for Disease Control and Prevention, told a conference in the southwestern city of Chengdu on Saturday.

China's top disease control official has said the efficacy of the country's Covid vaccines is low, in a rare admission of weakness.

a close up of a church: If you want a visa to China, you'll need a Chinese jab © Getty Images If you want a visa to China, you'll need a Chinese jab

In a press conference, Gao Fu added that China was considering mixing vaccines as a way of boosting efficacy.

China has developed four different vaccines approved for public use, though some trials abroad had suggested efficacy as low as 50%.

Mr Gao later said his comments had been misinterpreted.

More than 100 million people in China have received at least one shot of the vaccine.

Beijing insists the jabs are effective and said it will grant visas only to foreigners with a Chinese shot.

Official: Chinese vaccines' effectiveness low

  Official: Chinese vaccines' effectiveness low BEIJING (AP) — In a rare admission of the weakness of Chinese coronavirus vaccines, the country's top disease control official says their effectiveness is low and the government is considering mixing them to get a boost. Chinese vaccines “don’t have very high protection rates,” said the director of the China Centers for Disease Control, Gao Fu, at a conference Saturday in the southwestern city of Chengdu. Beijing has distributed hundreds of millions of doses abroad while trying to promote doubt about the effectiveness of the Pfizer-BioNTech vaccine made using the previously experimental messenger RNA, or mRNA, process.

What did Mr Fu say?

Gao Fu, head of the Chinese Centres for Disease Control and Prevention, on Saturday said at a conference the current vaccines "don't have very high rates of protection".

He suggested that the China was considering mixing Covid-19 vaccines, as a way of boosting efficacy.

Mr Gao explained that steps to "optimise" the vaccine process could include changing the number of doses and the length of time. He also suggested combining different vaccines for the immunization process.

But he later appeared to backtrack on his comments, telling state media Global Times that "protection rates of all vaccines in the world are sometimes high, and sometimes low".

"How to improve their efficacy is a question that needs to be considered by scientists around the world," he told the paper.

Doing business in China is difficult. A clash over human rights is making it harder

  Doing business in China is difficult. A clash over human rights is making it harder Companies that want to do business in China have long made compromises in the pursuit of success. Now an escalating diplomatic dispute over human rights is underscoring the stark choice facing Western executives: put profit or principles first. © Kevin Frayer/Getty Images BEIJING, CHINA - MARCH 25: People walk by the flagship store of clothing brand H&M at a shopping area on March 25, 2021 in Beijing, China. Many on Chinese social networking platforms called for boycotts of major Western brands, including H&M, after statements made by the companies in the past about Xinjiang cotton resurfaced online.


Video: China considers mixing COVID-19 vaccines (Reuters)

He added that his earlier admission that Chinese vaccines had a low protection rate were a "complete misunderstanding".

Mr Gao's original and later comments have been largely unreported by Chinese media.

His original comments however, attracted some criticism on social media site Weibo, with commenters suggesting that he should "stop talking".

What do we know about Chinese vaccines?

With little data released internationally, the effectiveness of the various Chinese vaccines has long been uncertain.

China's Sinovac vaccine for instance has shown in trials in Brazil to be only 50.4% effective, barely over the 50% threshold needed for regulatory approval by the World Health Organisation.

  • What do we know about China's Covid-19 vaccines?
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  • Coronavirus - what's gone wrong in Brazil?

Interim results from late-stage trials in Turkey and Indonesia however, have suggested the Sinovac shot to be between 91% and 65% effective.

Is China winning the vaccine diplomacy game?

  Is China winning the vaccine diplomacy game? Where producing countries send their vaccines has more to do with geopolitics, than with need.The country of 7 million, which is experiencing its biggest coronavirus wave yet, is short on vaccines. It could get them from China, except that would sour the Latin America’s country’s relations with the US—and Taiwan.

Western vaccines like the ones by BioNTech/Pfizer, Moderna or AstraZeneca all have an efficiency rate of around 90% or higher.

How are they different from other vaccines?

China's vaccines though differ significantly from some vaccines, especially those developed by Pfizer and Moderna.

Developed in a more traditional way, they are so-called inactivated vaccines which means they use killed viral particles to expose the immune system to the virus without risking a serious disease response.

By comparison, the BioNtech/Pfizer and Moderna vaccines are mRNA vaccines. This means part of the coronavirus' genetic code is injected into the body, training the immune system how to respond.

table © BBC

The UK's AstraZeneca vaccine is yet another type of vaccine where a version of a common cold virus from chimpanzees is modified to contain genetic material shared by the coronavirus. Once injected, it teaches the immune system how to fight the real virus.

One significant advantage of the Chinese vaccines is that it can be stored in standard refrigerators at 2-8 degrees Celsius. Moderna's vaccine needs to be stored at -20C and Pfizer's vaccine at -70C.

China is offering its vaccines around the world and has already shipped millions to countries from Indonesia, Turkey to Paraguay and Brazil.

Some US bishops discourage Catholics from getting Johnson & Johnson vaccine if others are available .
As officials and health experts race to get Americans vaccinated against Covid-19, some Catholic bishops have weighed in to discourage Church members from getting the latest, single-shot vaccine from Johnson & Johnson when alternatives are available. © Jay LaPrete/AP Ohio State University clinic manager Paige Blankenship, left, administers one of the first Johnson & Johnson Covid-19 vaccines on Tuesday.

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